Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study
Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflamm...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Ciências
2022-06-01
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| Series: | Anais da Academia Brasileira de Ciências |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300904&lng=en&tlng=en |
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| author | MARIA P.L. GALANTINI LORENA S. LEAL KARINE B. RODRIGUES ISRAEL S. RIBEIRO ITALO S. PEREIRA CAROLINE V. GONÇALVES STÉFANO P.M. CALADO DENISAR P. DOS SANTOS IGOR P.R. MUNIZ ROBSON A.A. DA SILVA |
| author_facet | MARIA P.L. GALANTINI LORENA S. LEAL KARINE B. RODRIGUES ISRAEL S. RIBEIRO ITALO S. PEREIRA CAROLINE V. GONÇALVES STÉFANO P.M. CALADO DENISAR P. DOS SANTOS IGOR P.R. MUNIZ ROBSON A.A. DA SILVA |
| author_sort | MARIA P.L. GALANTINI |
| collection | DOAJ |
| description | Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflammatory infiltrate in dermis. They presented greater weight, however, less amount of epididymal fat: the weight was increased while they had fat diminished. A positive correlation was observed between lipid content and bacterial load in mice trained at moderate intensity. Animals that were under high intensity exercises presented superior bacterial load on the lymph nodes, increased neutrophil count and circulating lymphocytes, and had leukocyte recruitment to the dermis augmented, when compared to the ones in moderate exercise. These findings suggest that moderate physical activity modulates the immune response in dermal infection caused by S. aureus in a murine model. |
| first_indexed | 2024-04-12T18:05:14Z |
| format | Article |
| id | doaj.art-6d2d9cd0fd134598a1d0c03a533fa1ee |
| institution | Directory Open Access Journal |
| issn | 1678-2690 |
| language | English |
| last_indexed | 2024-04-12T18:05:14Z |
| publishDate | 2022-06-01 |
| publisher | Academia Brasileira de Ciências |
| record_format | Article |
| series | Anais da Academia Brasileira de Ciências |
| spelling | doaj.art-6d2d9cd0fd134598a1d0c03a533fa1ee2022-12-22T03:22:01ZengAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências1678-26902022-06-0194210.1590/0001-3765202220200561Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot studyMARIA P.L. GALANTINIhttps://orcid.org/0000-0001-9423-5334LORENA S. LEALhttps://orcid.org/0000-0003-0059-9378KARINE B. RODRIGUEShttps://orcid.org/0000-0003-1465-5895ISRAEL S. RIBEIROhttps://orcid.org/0000-0002-1262-1387ITALO S. PEREIRAhttps://orcid.org/0000-0001-5697-5673CAROLINE V. GONÇALVEShttps://orcid.org/0000-0003-0895-1583STÉFANO P.M. CALADOhttps://orcid.org/0000-0003-3458-1328DENISAR P. DOS SANTOShttps://orcid.org/0000-0002-3930-9510IGOR P.R. MUNIZhttps://orcid.org/0000-0003-1842-6432ROBSON A.A. DA SILVAhttps://orcid.org/0000-0003-1361-1591Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflammatory infiltrate in dermis. They presented greater weight, however, less amount of epididymal fat: the weight was increased while they had fat diminished. A positive correlation was observed between lipid content and bacterial load in mice trained at moderate intensity. Animals that were under high intensity exercises presented superior bacterial load on the lymph nodes, increased neutrophil count and circulating lymphocytes, and had leukocyte recruitment to the dermis augmented, when compared to the ones in moderate exercise. These findings suggest that moderate physical activity modulates the immune response in dermal infection caused by S. aureus in a murine model.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300904&lng=en&tlng=eninfectionmicephysical exerciseStaphylococcus aureus |
| spellingShingle | MARIA P.L. GALANTINI LORENA S. LEAL KARINE B. RODRIGUES ISRAEL S. RIBEIRO ITALO S. PEREIRA CAROLINE V. GONÇALVES STÉFANO P.M. CALADO DENISAR P. DOS SANTOS IGOR P.R. MUNIZ ROBSON A.A. DA SILVA Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study Anais da Academia Brasileira de Ciências infection mice physical exercise Staphylococcus aureus |
| title | Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
| title_full | Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
| title_fullStr | Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
| title_full_unstemmed | Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
| title_short | Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
| title_sort | physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training a pilot study |
| topic | infection mice physical exercise Staphylococcus aureus |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300904&lng=en&tlng=en |
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