The Cytoplasmic Domains of Streptococcus mutans Membrane Protein Insertases YidC1 and YidC2 Confer Unique Structural and Functional Attributes to Each Paralog

The Cytoplasmic Domains of Streptococcus mutans Membrane Protein Insertases YidC1 and YidC2 Confer Unique Structural and Functional Attributes to Each Paralog

Integral and membrane-anchored proteins are pivotal to survival and virulence of the dental pathogen, Streptococcus mutans. The bacterial chaperone/insertase, YidC, contributes to membrane protein translocation. Unlike Escherichia coli, most Gram-positive bacteria contain two YidC paralogs. Herein,...

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Bibliographic Details
Main Authors: Surabhi Mishra, L. Jeannine Brady
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Microbiology
Subjects:
structure-function
YidC
Streptococcus mutans
insertase
paralogs
bacterial stress tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.760873/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.760873/full

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