Biocompatible topical delivery system of high-molecular-weight hyaluronan into human stratum corneum using magnesium chloride

Biocompatible topical delivery system of high-molecular-weight hyaluronan into human stratum corneum using magnesium chloride

Abstract Non-invasive delivery of hyaluronan into the stratum corneum (SC) is extremely difficult because of its high molecular weight and the strong barrier of the SC. We developed a safe method of administering hyaluronan into the human SC and determined its penetration route. The amount of hyalur...

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Bibliographic Details
Main Authors:	Mika Y. Fujii, Anna Okishima, Hiroko S. Ichiwata, Takashi Oka
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-07-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-37718-5

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