Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variants.

Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variants.

Nef is an accessory viral protein that promotes HIV-1 replication, facilitating alterations in cellular pathways via multiple protein-protein interactions. The advent of proteomics has expanded the focus on better identification of novel molecular pathways regulating disease progression. In this stu...

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Bibliographic Details
Main Authors: Reshu Saxena, Sudipti Gupta, Kavita Singh, Kalyan Mitra, Anil Kumar Tripathi, Raj Kamal Tripathi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395413?pdf=render

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