The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical comp...

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Bibliographic Details
Main Authors: François Pognan, Thomas Steger-Hartmann, Carlos Díaz, Niklas Blomberg, Frank Bringezu, Katharine Briggs, Giulia Callegaro, Salvador Capella-Gutierrez, Emilio Centeno, Javier Corvi, Philip Drew, William C. Drewe, José M. Fernández, Laura I. Furlong, Emre Guney, Jan A. Kors, Miguel Angel Mayer, Manuel Pastor, Janet Piñero, Juan Manuel Ramírez-Anguita, Francesco Ronzano, Philip Rowell, Josep Saüch-Pitarch, Alfonso Valencia, Bob van de Water, Johan van der Lei, Erik van Mulligen, Ferran Sanz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceuticals
Subjects:
toxicology
drug safety
translational safety assessment
data sharing
integrative knowledge management
data mining
Online Access:https://www.mdpi.com/1424-8247/14/3/237
Description
Summary:eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.
ISSN:1424-8247

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