Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells.

Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells.

Inhalation of Aspergillus fumigatus conidia can cause severe aspergillosis in immunosuppressed people. A. fumigatus produces a large number of secondary metabolites, some of which are airborne by conidia and whose toxicity to the respiratory tract has not been investigated. We found that spores of A...

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Bibliographic Details
Main Authors: Thierry Gauthier, Xiaodi Wang, Joice Sifuentes Dos Santos, Athanasios Fysikopoulos, Souria Tadrist, Cécile Canlet, Marie Pierre Artigot, Nicolas Loiseau, Isabelle P Oswald, Olivier Puel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3272003?pdf=render

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