Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution

Abstract Background Since late 2019, a severe acute respiratory syndrome, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread with overwhelming speed causing over 214 million confirmed infections and more than 4.5 million deaths worldwide. In this framework, Italy...

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Main Authors: Alessandro De Cassai, Federico Longhini, Stefano Romagnoli, Fabio Cavaliere, Antonio Caroleo, Lorenzo Foti, Elisa Furlani, Sara Gianoli, Francesco Monteleone, Giuseppe Saraco, Gianluca Villa, Giorgio Conti, Paolo Navalesi
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Anesthesia, Analgesia and Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s44158-021-00017-4
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author Alessandro De Cassai
Federico Longhini
Stefano Romagnoli
Fabio Cavaliere
Antonio Caroleo
Lorenzo Foti
Elisa Furlani
Sara Gianoli
Francesco Monteleone
Giuseppe Saraco
Gianluca Villa
Giorgio Conti
Paolo Navalesi
author_facet Alessandro De Cassai
Federico Longhini
Stefano Romagnoli
Fabio Cavaliere
Antonio Caroleo
Lorenzo Foti
Elisa Furlani
Sara Gianoli
Francesco Monteleone
Giuseppe Saraco
Gianluca Villa
Giorgio Conti
Paolo Navalesi
author_sort Alessandro De Cassai
collection DOAJ
description Abstract Background Since late 2019, a severe acute respiratory syndrome, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread with overwhelming speed causing over 214 million confirmed infections and more than 4.5 million deaths worldwide. In this framework, Italy had the second highest number of SARS-CoV-2 infections worldwide, and the largest number of deaths. A global effort of both the scientific community and governments has been undertaken to stem the pandemic. The aim of this paper is to perform a narrative review of the Italian contribution to the scientific literature regarding intensive care management of patients suffering from COVID-19, being one of the first western countries to face an outbreak of SARS-CoV-2 infection. Main body We performed a narrative review of the literature, dedicating particular attention and a dedicated paragraph to ventilatory support management, chest imaging findings, biomarkers, possible pharmacological interventions, bacterial superinfections, prognosis and non-clinical key aspects such as communication and interaction with relatives. Conclusions Many colleagues, nurses and patients died leaving their families alone. To all of them, we send our thoughts and dedicate these pages.
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spelling doaj.art-6d371f7ee00349e3a8696ffcb0a2bccd2022-12-22T02:37:15ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862021-11-011111310.1186/s44158-021-00017-4Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contributionAlessandro De Cassai0Federico Longhini1Stefano Romagnoli2Fabio Cavaliere3Antonio Caroleo4Lorenzo Foti5Elisa Furlani6Sara Gianoli7Francesco Monteleone8Giuseppe Saraco9Gianluca Villa10Giorgio Conti11Paolo Navalesi12Anesthesia and Intensive Care Unit, University Hospital of PaduaAnesthesia and Intensive Care, “Mater Domini” University Hospital, Department of Medical and Surgical Sciences, “Magna Graecia” UniversityDepartment of Health Science, Section of Anaesthesia and Critical Care, University of FlorenceDepartment of Medicine-DIMED, University of PaduaAnesthesia and Intensive Care, “Mater Domini” University Hospital, Department of Medical and Surgical Sciences, “Magna Graecia” UniversityDepartment of Health Science, Section of Anaesthesia and Critical Care, University of FlorenceDepartment of Medicine-DIMED, University of PaduaDepartment of Medicine-DIMED, University of PaduaDepartment of Medicine-DIMED, University of PaduaAnesthesia and Intensive Care, “Mater Domini” University Hospital, Department of Medical and Surgical Sciences, “Magna Graecia” UniversityDepartment of Health Science, Section of Anaesthesia and Critical Care, University of FlorenceDepartment of Anesthesia and Intensive Care, Fondazione Policlinico A. Gemelli IRCCSAnesthesia and Intensive Care Unit, University Hospital of PaduaAbstract Background Since late 2019, a severe acute respiratory syndrome, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread with overwhelming speed causing over 214 million confirmed infections and more than 4.5 million deaths worldwide. In this framework, Italy had the second highest number of SARS-CoV-2 infections worldwide, and the largest number of deaths. A global effort of both the scientific community and governments has been undertaken to stem the pandemic. The aim of this paper is to perform a narrative review of the Italian contribution to the scientific literature regarding intensive care management of patients suffering from COVID-19, being one of the first western countries to face an outbreak of SARS-CoV-2 infection. Main body We performed a narrative review of the literature, dedicating particular attention and a dedicated paragraph to ventilatory support management, chest imaging findings, biomarkers, possible pharmacological interventions, bacterial superinfections, prognosis and non-clinical key aspects such as communication and interaction with relatives. Conclusions Many colleagues, nurses and patients died leaving their families alone. To all of them, we send our thoughts and dedicate these pages.https://doi.org/10.1186/s44158-021-00017-4COVID-19SARS-COV 2ItalyReview
spellingShingle Alessandro De Cassai
Federico Longhini
Stefano Romagnoli
Fabio Cavaliere
Antonio Caroleo
Lorenzo Foti
Elisa Furlani
Sara Gianoli
Francesco Monteleone
Giuseppe Saraco
Gianluca Villa
Giorgio Conti
Paolo Navalesi
Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
Journal of Anesthesia, Analgesia and Critical Care
COVID-19
SARS-COV 2
Italy
Review
title Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
title_full Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
title_fullStr Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
title_full_unstemmed Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
title_short Research on SARS-COV-2 pandemic: a narrative review focused on the Italian contribution
title_sort research on sars cov 2 pandemic a narrative review focused on the italian contribution
topic COVID-19
SARS-COV 2
Italy
Review
url https://doi.org/10.1186/s44158-021-00017-4
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