Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance

Background: Many cardiac diseases can cause cardiac hypertrophy developed by the established cardiac overload, such as long term of uncontrolled hypertension, valvuler disease or congenital anomaly and many more causes. If the cause of hypertrophy persists for long time it will generate heart failur...

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Main Authors: Durra A. Ahmed, Mutaz F. Hussain, Anmar Z. Saleh
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2013-07-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/640
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author Durra A. Ahmed
Mutaz F. Hussain
Anmar Z. Saleh
author_facet Durra A. Ahmed
Mutaz F. Hussain
Anmar Z. Saleh
author_sort Durra A. Ahmed
collection DOAJ
description Background: Many cardiac diseases can cause cardiac hypertrophy developed by the established cardiac overload, such as long term of uncontrolled hypertension, valvuler disease or congenital anomaly and many more causes. If the cause of hypertrophy persists for long time it will generate heart failure, as a result changes in size, shape and function of the heart which refer as remodeling. Objective: To investigate the types of remodeling in patients with heart failure, and study its relation with cardiac performance. Patients and methods: The study included fifty normal individuals and fifty patients, only those patients who developed hypertrophy and failure were chosen. The study has included the measurements of many cardiac parameters obtained by the echocardiography examination. The measurements have included: Left ventricle internal diameter at diastole (LVIDd), Left ventricle internal diameter at systole ( LVIDs), Peak velocity of early transmitral flow (E), Peak velocity of late transmitral flow (A), Isovolumetric contraction time (ICT), Isovolumetric relaxation time (IRT), Ejection time (ET), Ejection fraction (EF%), myocardial performance Index (MPI), Left ventricle mass index (LVMI ), Posterior wall thickness at diastole ( PWTd), Relative wall thickness ( RWT) and Interventricular septum thickness at diastole (IVSTd). Results: results of remodeling have shown nine patients expressed concentric hypertrophy, thirty seven patients have shown eccentric hypertrophy and only four patients were similar to normal. Many other changes were observed these are an exaggerated ratio of (E/A) goes up to four, an increase in the (LV) volume appeared on its dimension at systole for patients (54.63%), a reduced cardiac output for patients and insignificant small change in relative wall thickness (RWT). Conclusion: In conclusion long term cardiac overload can induce hypertrophy, after a period of time heart failure may ensue. This can influence the shape and size of the heart together with a reduction in its performance.
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spelling doaj.art-6d3b652409534dfc99623eab0b98696a2024-02-02T22:19:27ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572013-07-0155210.32007/jfacmedbagdad.v2125-130%Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac PerformanceDurra A. Ahmed0Mutaz F. Hussain1Anmar Z. Saleh2Medical Physics, college of Medicine, Baghdad University.Dept. of Medicine, College of Medicine, Baghdad University.Medical Physics, college of Medicine, Baghdad University.Background: Many cardiac diseases can cause cardiac hypertrophy developed by the established cardiac overload, such as long term of uncontrolled hypertension, valvuler disease or congenital anomaly and many more causes. If the cause of hypertrophy persists for long time it will generate heart failure, as a result changes in size, shape and function of the heart which refer as remodeling. Objective: To investigate the types of remodeling in patients with heart failure, and study its relation with cardiac performance. Patients and methods: The study included fifty normal individuals and fifty patients, only those patients who developed hypertrophy and failure were chosen. The study has included the measurements of many cardiac parameters obtained by the echocardiography examination. The measurements have included: Left ventricle internal diameter at diastole (LVIDd), Left ventricle internal diameter at systole ( LVIDs), Peak velocity of early transmitral flow (E), Peak velocity of late transmitral flow (A), Isovolumetric contraction time (ICT), Isovolumetric relaxation time (IRT), Ejection time (ET), Ejection fraction (EF%), myocardial performance Index (MPI), Left ventricle mass index (LVMI ), Posterior wall thickness at diastole ( PWTd), Relative wall thickness ( RWT) and Interventricular septum thickness at diastole (IVSTd). Results: results of remodeling have shown nine patients expressed concentric hypertrophy, thirty seven patients have shown eccentric hypertrophy and only four patients were similar to normal. Many other changes were observed these are an exaggerated ratio of (E/A) goes up to four, an increase in the (LV) volume appeared on its dimension at systole for patients (54.63%), a reduced cardiac output for patients and insignificant small change in relative wall thickness (RWT). Conclusion: In conclusion long term cardiac overload can induce hypertrophy, after a period of time heart failure may ensue. This can influence the shape and size of the heart together with a reduction in its performance.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/640Heart Failure, Cardiac remodeling & left ventricular performance.
spellingShingle Durra A. Ahmed
Mutaz F. Hussain
Anmar Z. Saleh
Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
مجلة كلية الطب
Heart Failure, Cardiac remodeling & left ventricular performance.
title Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
title_full Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
title_fullStr Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
title_full_unstemmed Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
title_short Left Ventricle Remodeling for Patients with Heart Failure and its Influence on Cardiac Performance
title_sort left ventricle remodeling for patients with heart failure and its influence on cardiac performance
topic Heart Failure, Cardiac remodeling & left ventricular performance.
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/640
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