Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans
Abstract Background Enchondromas (EC) and atypical cartilaginous tumours (ACT) of the knee joint represent benign/intermediate chondromatous neoplasms of the bone that are most commonly discovered incidentally. Based on small to intermediate-sized cohorts, the prevalence of cartilaginous tumours of...
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | Cancer Imaging |
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| Online Access: | https://doi.org/10.1186/s40644-023-00572-9 |
| _version_ | 1797817775878569984 |
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| author | Johannes Nikolaus Woltsche Maria Anna Smolle Dieter Szolar Marko Bergovec Andreas Leithner |
| author_facet | Johannes Nikolaus Woltsche Maria Anna Smolle Dieter Szolar Marko Bergovec Andreas Leithner |
| author_sort | Johannes Nikolaus Woltsche |
| collection | DOAJ |
| description | Abstract Background Enchondromas (EC) and atypical cartilaginous tumours (ACT) of the knee joint represent benign/intermediate chondromatous neoplasms of the bone that are most commonly discovered incidentally. Based on small to intermediate-sized cohorts, the prevalence of cartilaginous tumours of the knee as visible in MRI is estimated at 0.2–2.9%. This study aimed at verifying/challenging these numbers via retrospective examination of a larger, uniform patient cohort. Methods Between 01.01.2007 and 01.03.2020, 44,762 patients had received an MRI of the knee for any indication at a radiologic centre. Of these, 697 patients presented with MRI reports positive for cartilaginous lesions. In a three-step workflow, 46 patients were excluded by a trained co-author, a radiologist and an orthopaedic oncologist, as wrongly being diagnosed for a cartilage tumour. Results Of 44,762 patients, 651 presented with at least one EC/ACT indicating a prevalence of 1.45% for benign/intermediate cartilaginous tumours of the knee joint (EC: 1.4%; ACTs: 0.05%). As 21 patients showed 2 chondromatous lesions, altogether 672 tumours (650 ECs [96.7%] and 22 ACTs [3.3%]) could be analysed in terms of tumour characteristics: With a mean size of 1.6 ± 1.1 cm, most lesions were located in the distal femur (72.9%), in the metaphysis of the respective bone (58.9%) and centrally in the medullary canal (57.4%). Conclusions This study revealed an overall prevalence of 1.45% for cartilage lesions around the knee joint. Whilst a constant increase in prevalence was found for ECs over 13.2 years, prevalence remained constant for ACTs. |
| first_indexed | 2024-03-13T08:59:24Z |
| format | Article |
| id | doaj.art-6d3d048215404e978d18e013752b9f82 |
| institution | Directory Open Access Journal |
| issn | 1470-7330 |
| language | English |
| last_indexed | 2024-03-13T08:59:24Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Cancer Imaging |
| spelling | doaj.art-6d3d048215404e978d18e013752b9f822023-05-28T11:26:34ZengBMCCancer Imaging1470-73302023-05-012311910.1186/s40644-023-00572-9Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scansJohannes Nikolaus Woltsche0Maria Anna Smolle1Dieter Szolar2Marko Bergovec3Andreas Leithner4Department of Orthopaedics and Trauma, Medical University of GrazDepartment of Orthopaedics and Trauma, Medical University of GrazDiagnostikum GrazDepartment of Orthopaedics and Trauma, Medical University of GrazDepartment of Orthopaedics and Trauma, Medical University of GrazAbstract Background Enchondromas (EC) and atypical cartilaginous tumours (ACT) of the knee joint represent benign/intermediate chondromatous neoplasms of the bone that are most commonly discovered incidentally. Based on small to intermediate-sized cohorts, the prevalence of cartilaginous tumours of the knee as visible in MRI is estimated at 0.2–2.9%. This study aimed at verifying/challenging these numbers via retrospective examination of a larger, uniform patient cohort. Methods Between 01.01.2007 and 01.03.2020, 44,762 patients had received an MRI of the knee for any indication at a radiologic centre. Of these, 697 patients presented with MRI reports positive for cartilaginous lesions. In a three-step workflow, 46 patients were excluded by a trained co-author, a radiologist and an orthopaedic oncologist, as wrongly being diagnosed for a cartilage tumour. Results Of 44,762 patients, 651 presented with at least one EC/ACT indicating a prevalence of 1.45% for benign/intermediate cartilaginous tumours of the knee joint (EC: 1.4%; ACTs: 0.05%). As 21 patients showed 2 chondromatous lesions, altogether 672 tumours (650 ECs [96.7%] and 22 ACTs [3.3%]) could be analysed in terms of tumour characteristics: With a mean size of 1.6 ± 1.1 cm, most lesions were located in the distal femur (72.9%), in the metaphysis of the respective bone (58.9%) and centrally in the medullary canal (57.4%). Conclusions This study revealed an overall prevalence of 1.45% for cartilage lesions around the knee joint. Whilst a constant increase in prevalence was found for ECs over 13.2 years, prevalence remained constant for ACTs.https://doi.org/10.1186/s40644-023-00572-9EnchondromaAtypical cartilaginous tumourPrevalenceKnee jointMRI |
| spellingShingle | Johannes Nikolaus Woltsche Maria Anna Smolle Dieter Szolar Marko Bergovec Andreas Leithner Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans Cancer Imaging Enchondroma Atypical cartilaginous tumour Prevalence Knee joint MRI |
| title | Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans |
| title_full | Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans |
| title_fullStr | Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans |
| title_full_unstemmed | Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans |
| title_short | Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans |
| title_sort | prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on mri scans |
| topic | Enchondroma Atypical cartilaginous tumour Prevalence Knee joint MRI |
| url | https://doi.org/10.1186/s40644-023-00572-9 |
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