Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina
Introduction: Unstable angina as a clinical condition includes a major group of patients manifested with acute coronary syndrome. Misdiagnosis of this clinical syndrome causes myocardial infarction (MI) and death. Conventional and advanced forms of treatment are used with the aim of rapid stabilizat...
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| Format: | Article |
| Language: | fas |
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Shahid Sadoughi University of Medical Sciences
2007-12-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| Subjects: | |
| Online Access: | http://jssu.ssu.ac.ir/browse.php?a_id=643&slc_lang=en&sid=1&ftxt=1 |
| _version_ | 1811284540643082240 |
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| author | A Azimi MR Azimi M Motafakker M Sadr-Bafghi A Andishmand |
| author_facet | A Azimi MR Azimi M Motafakker M Sadr-Bafghi A Andishmand |
| author_sort | A Azimi |
| collection | DOAJ |
| description | Introduction: Unstable angina as a clinical condition includes a major group of patients manifested with acute coronary syndrome. Misdiagnosis of this clinical syndrome causes myocardial infarction (MI) and death. Conventional and advanced forms of treatment are used with the aim of rapid stabilization of unstable angina. Although infusion of glucose - insulin - potassium (GIK) solution has had good results in acute MI, no major trial has studied its effect in unstable angina. The main goal of this study was evaluation of the effectiveness of GIK solution on prognosis of hospitalized unstable angina patients. Methods: This randomized clinical trial included patients with class II and III unstable angina (two groups of 94 patients, each ) with a mean age of 62.47±13.20 years and Female /Male ratio of 1.35 admitted in the CCU’s of Yazd from September 2003 to May 2004 . Results: There was no significant difference between the study and control groups regarding mean age, sex ratio and unstable angina class (P=0.15, P=0.77 and P=0.76). The study group had significant reduction in recurrent chest pain and duration of hospitalization (P=0.001 and P=0.02). The most common adverse effect of GIK solution was pain at infusion site. Conclusion: Use of GIK solution causes early stabilization of unstable angina patients without any significant or life threatening adverse effect. |
| first_indexed | 2024-04-13T02:31:14Z |
| format | Article |
| id | doaj.art-6d3ea81ad71448c7a3e7c70090b2431a |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-04-13T02:31:14Z |
| publishDate | 2007-12-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-6d3ea81ad71448c7a3e7c70090b2431a2022-12-22T03:06:35ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332007-12-011531419Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable AnginaA AzimiMR AzimiM MotafakkerM Sadr-BafghiA AndishmandIntroduction: Unstable angina as a clinical condition includes a major group of patients manifested with acute coronary syndrome. Misdiagnosis of this clinical syndrome causes myocardial infarction (MI) and death. Conventional and advanced forms of treatment are used with the aim of rapid stabilization of unstable angina. Although infusion of glucose - insulin - potassium (GIK) solution has had good results in acute MI, no major trial has studied its effect in unstable angina. The main goal of this study was evaluation of the effectiveness of GIK solution on prognosis of hospitalized unstable angina patients. Methods: This randomized clinical trial included patients with class II and III unstable angina (two groups of 94 patients, each ) with a mean age of 62.47±13.20 years and Female /Male ratio of 1.35 admitted in the CCU’s of Yazd from September 2003 to May 2004 . Results: There was no significant difference between the study and control groups regarding mean age, sex ratio and unstable angina class (P=0.15, P=0.77 and P=0.76). The study group had significant reduction in recurrent chest pain and duration of hospitalization (P=0.001 and P=0.02). The most common adverse effect of GIK solution was pain at infusion site. Conclusion: Use of GIK solution causes early stabilization of unstable angina patients without any significant or life threatening adverse effect.http://jssu.ssu.ac.ir/browse.php?a_id=643&slc_lang=en&sid=1&ftxt=1Glucose - Insulin – Potassium (GIK)Unstable angina |
| spellingShingle | A Azimi MR Azimi M Motafakker M Sadr-Bafghi A Andishmand Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Glucose - Insulin – Potassium (GIK) Unstable angina |
| title | Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina |
| title_full | Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina |
| title_fullStr | Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina |
| title_full_unstemmed | Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina |
| title_short | Effect of Glucose - Insulin - Potassium (Gik) Solution on Short Term Prognosis of Unstable Angina |
| title_sort | effect of glucose insulin potassium gik solution on short term prognosis of unstable angina |
| topic | Glucose - Insulin – Potassium (GIK) Unstable angina |
| url | http://jssu.ssu.ac.ir/browse.php?a_id=643&slc_lang=en&sid=1&ftxt=1 |
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