Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart
A 68-year-old female with end-stage heart failure presented to the hospital for heart transplant. She was diagnosed with achalasia 14 months prior and treated with frequent botulinum toxin injections. She underwent orthotopic heart transplant on the day of admission and was extubated a few days late...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2022-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2022/2054727 |
| _version_ | 1811182663676985344 |
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| author | Amanda Fernandes Crystal Lihong Yan Phillip Ruiz Nina Thakkar Rivera |
| author_facet | Amanda Fernandes Crystal Lihong Yan Phillip Ruiz Nina Thakkar Rivera |
| author_sort | Amanda Fernandes |
| collection | DOAJ |
| description | A 68-year-old female with end-stage heart failure presented to the hospital for heart transplant. She was diagnosed with achalasia 14 months prior and treated with frequent botulinum toxin injections. She underwent orthotopic heart transplant on the day of admission and was extubated a few days later. She developed intractable nausea and vomiting. Her first endomyocardial biopsy revealed moderate, approaching severe rejection. She was treated with high-dose intravenous pulse steroids. Fluoroscopy at the time of follow-up biopsy showed undigested pills in her esophagus with narrowing at the distal end and thus failure to deliver immunosuppressive therapy. This case highlights achalasia as an etiology for acute rejection and its potential management. |
| first_indexed | 2024-04-11T09:35:39Z |
| format | Article |
| id | doaj.art-6d3f492a83184d1489b94bd704f8891c |
| institution | Directory Open Access Journal |
| issn | 2090-6412 |
| language | English |
| last_indexed | 2024-04-11T09:35:39Z |
| publishDate | 2022-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj.art-6d3f492a83184d1489b94bd704f8891c2022-12-22T04:31:44ZengHindawi LimitedCase Reports in Cardiology2090-64122022-01-01202210.1155/2022/2054727Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted HeartAmanda Fernandes0Crystal Lihong Yan1Phillip Ruiz2Nina Thakkar Rivera3Division of Internal MedicineDivision of Internal MedicineDepartments of Surgery and PathologyDivision of CardiologyA 68-year-old female with end-stage heart failure presented to the hospital for heart transplant. She was diagnosed with achalasia 14 months prior and treated with frequent botulinum toxin injections. She underwent orthotopic heart transplant on the day of admission and was extubated a few days later. She developed intractable nausea and vomiting. Her first endomyocardial biopsy revealed moderate, approaching severe rejection. She was treated with high-dose intravenous pulse steroids. Fluoroscopy at the time of follow-up biopsy showed undigested pills in her esophagus with narrowing at the distal end and thus failure to deliver immunosuppressive therapy. This case highlights achalasia as an etiology for acute rejection and its potential management.http://dx.doi.org/10.1155/2022/2054727 |
| spellingShingle | Amanda Fernandes Crystal Lihong Yan Phillip Ruiz Nina Thakkar Rivera Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart Case Reports in Cardiology |
| title | Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart |
| title_full | Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart |
| title_fullStr | Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart |
| title_full_unstemmed | Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart |
| title_short | Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart |
| title_sort | achalasia as an unusual cause of acute cellular rejection of a transplanted heart |
| url | http://dx.doi.org/10.1155/2022/2054727 |
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