Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala

Limbic encephalitis (LE), a rare cause of encephalitis, generally presents with neuropsychiatric manifestations, memory deficits, seizures, and movement disorders. The case of a 41-year-old female patient with LE involving the left amygdala is presented. The patient was admitted to the emergency de...

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Main Authors: Asuman Orhan Varoglu, Hasan Turan Karatepe
Format: Article
Language:English
Published: Pakistan Medical Association 2022-04-01
Series:Journal of the Pakistan Medical Association
Online Access:https://www.ojs.jpma.org.pk/index.php/public_html/article/view/4480
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author Asuman Orhan Varoglu
Hasan Turan Karatepe
author_facet Asuman Orhan Varoglu
Hasan Turan Karatepe
author_sort Asuman Orhan Varoglu
collection DOAJ
description Limbic encephalitis (LE), a rare cause of encephalitis, generally presents with neuropsychiatric manifestations, memory deficits, seizures, and movement disorders. The case of a 41-year-old female patient with LE involving the left amygdala is presented. The patient was admitted to the emergency department with complaints of unconsciousness and seizures. Paraneoplastic and limbic markers were negative. This case was diagnosed as seronegative LE. Three to four months after the diagnosis, it was observed that her sexual preference changed to the female sex. No report has been published so far, concerning any case of LE associated with changes in sexual behaviour. The patient was treated with intravenous methylprednisolone (IVP) and triple antiepileptic therapy. After treatment, changes in sexual behaviour returned to the previous state. Keywords: limbic encephalitis, sexual behaviour, autoimmune encephalitis, paraneoplastic syndrome, left amygdala, homosexual.
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spelling doaj.art-6d41312e996745b1b27e7e91e3a909f82023-05-25T04:22:15ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822022-04-0172810.47391/JPMA.4480Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdalaAsuman Orhan Varoglu0Hasan Turan Karatepe1Department of Neurology, Medical School, Istanbul Medeniyet University, Istanbul, TurkeyDepartment of Psychiatry, Medical School, Istanbul Medeniyet University, Istanbul, Turkey Limbic encephalitis (LE), a rare cause of encephalitis, generally presents with neuropsychiatric manifestations, memory deficits, seizures, and movement disorders. The case of a 41-year-old female patient with LE involving the left amygdala is presented. The patient was admitted to the emergency department with complaints of unconsciousness and seizures. Paraneoplastic and limbic markers were negative. This case was diagnosed as seronegative LE. Three to four months after the diagnosis, it was observed that her sexual preference changed to the female sex. No report has been published so far, concerning any case of LE associated with changes in sexual behaviour. The patient was treated with intravenous methylprednisolone (IVP) and triple antiepileptic therapy. After treatment, changes in sexual behaviour returned to the previous state. Keywords: limbic encephalitis, sexual behaviour, autoimmune encephalitis, paraneoplastic syndrome, left amygdala, homosexual. https://www.ojs.jpma.org.pk/index.php/public_html/article/view/4480
spellingShingle Asuman Orhan Varoglu
Hasan Turan Karatepe
Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
Journal of the Pakistan Medical Association
title Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
title_full Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
title_fullStr Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
title_full_unstemmed Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
title_short Sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
title_sort sexual behaviour change in seronegative limbic encephalitis due to the involvement of the left amygdala
url https://www.ojs.jpma.org.pk/index.php/public_html/article/view/4480
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AT hasanturankaratepe sexualbehaviourchangeinseronegativelimbicencephalitisduetotheinvolvementoftheleftamygdala