Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo
Photoacoustic microscopy (PAM) is used to visualize blood vessels and to monitor their time-dependent changes. Photoplethysmography (PPG) measures hemodynamic time-series changes such as heart rate. However, PPG’s limited visual access to the dynamic changes of blood vessels has prohibited further u...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-09-01
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| Series: | Photoacoustics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213597922000398 |
| _version_ | 1828356296726806528 |
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| author | Joongho Ahn Jin Woo Baik Yeonggeon Kim Karam Choi Jeongwoo Park Hyojin Kim Jin Young Kim Hyung Ham Kim Sung Hyun Nam Chulhong Kim |
| author_facet | Joongho Ahn Jin Woo Baik Yeonggeon Kim Karam Choi Jeongwoo Park Hyojin Kim Jin Young Kim Hyung Ham Kim Sung Hyun Nam Chulhong Kim |
| author_sort | Joongho Ahn |
| collection | DOAJ |
| description | Photoacoustic microscopy (PAM) is used to visualize blood vessels and to monitor their time-dependent changes. Photoplethysmography (PPG) measures hemodynamic time-series changes such as heart rate. However, PPG’s limited visual access to the dynamic changes of blood vessels has prohibited further understanding of hemodynamics. Here, we propose a novel, fully integrated PAM and photoplethysmography (PAM-PPG) system to understand hemodynamic features in detail. Using the PAM-PPG system, we simultaneously acquire vascular images (by PAM) and changes in the blood volume (by PPG) from human fingers. Next, we determine the heart rate from changes in the PA signals, which match well with the PPG signals. These changes can be measured if the blood flow is not blocked. From the results, we believe that PAM-PPG could be a useful clinical tool in various clinical fields such as cardiology and endocrinology. |
| first_indexed | 2024-04-14T02:56:58Z |
| format | Article |
| id | doaj.art-6d4232b0e3584f84b8669d9119b6803b |
| institution | Directory Open Access Journal |
| issn | 2213-5979 |
| language | English |
| last_indexed | 2024-04-14T02:56:58Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photoacoustics |
| spelling | doaj.art-6d4232b0e3584f84b8669d9119b6803b2022-12-22T02:16:04ZengElsevierPhotoacoustics2213-59792022-09-0127100374Fully integrated photoacoustic microscopy and photoplethysmography of human in vivoJoongho Ahn0Jin Woo Baik1Yeonggeon Kim2Karam Choi3Jeongwoo Park4Hyojin Kim5Jin Young Kim6Hyung Ham Kim7Sung Hyun Nam8Chulhong Kim9Departments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaSamsung Advanced Institute of Technology, Samsung Electronics Co. Ltd., Suwon-si, Gyeonggi-do 16678, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaDepartments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of KoreaSamsung Advanced Institute of Technology, Samsung Electronics Co. Ltd., Suwon-si, Gyeonggi-do 16678, Republic of Korea; Corresponding authors.Departments of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do 37673, Republic of Korea; Corresponding authors.Photoacoustic microscopy (PAM) is used to visualize blood vessels and to monitor their time-dependent changes. Photoplethysmography (PPG) measures hemodynamic time-series changes such as heart rate. However, PPG’s limited visual access to the dynamic changes of blood vessels has prohibited further understanding of hemodynamics. Here, we propose a novel, fully integrated PAM and photoplethysmography (PAM-PPG) system to understand hemodynamic features in detail. Using the PAM-PPG system, we simultaneously acquire vascular images (by PAM) and changes in the blood volume (by PPG) from human fingers. Next, we determine the heart rate from changes in the PA signals, which match well with the PPG signals. These changes can be measured if the blood flow is not blocked. From the results, we believe that PAM-PPG could be a useful clinical tool in various clinical fields such as cardiology and endocrinology.http://www.sciencedirect.com/science/article/pii/S2213597922000398Blood vesselVascular movementBlood volume changePulsationHeartbeat |
| spellingShingle | Joongho Ahn Jin Woo Baik Yeonggeon Kim Karam Choi Jeongwoo Park Hyojin Kim Jin Young Kim Hyung Ham Kim Sung Hyun Nam Chulhong Kim Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo Photoacoustics Blood vessel Vascular movement Blood volume change Pulsation Heartbeat |
| title | Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| title_full | Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| title_fullStr | Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| title_full_unstemmed | Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| title_short | Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| title_sort | fully integrated photoacoustic microscopy and photoplethysmography of human in vivo |
| topic | Blood vessel Vascular movement Blood volume change Pulsation Heartbeat |
| url | http://www.sciencedirect.com/science/article/pii/S2213597922000398 |
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