Platelet volume indices in gestational hypertension: An observational study
Background & Objectives: The incidence of gestational hypertension is increasing in India which accounts for various maternal morbidity & mortality. As gestational hypertension is hypercogulability state we wanted to assess platelet volume indices in gestational hypertension. Materials and M...
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| Format: | Article |
| Language: | English |
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Al Ameen Medical College
2023-01-01
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| Series: | Al Ameen Journal of Medical Sciences |
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| Online Access: | http://ajms.alameenmedical.org/ArticlePDFs/4%20AJMS%20V16.N1.2023%20p%2012-17.pdf |
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| author | Nagalakshmi Vijaykumar Deepti Dixit Sanjivani S. Jadhav Asha Neravi Usha Kiran Naidu Rishab Patil |
| author_facet | Nagalakshmi Vijaykumar Deepti Dixit Sanjivani S. Jadhav Asha Neravi Usha Kiran Naidu Rishab Patil |
| author_sort | Nagalakshmi Vijaykumar |
| collection | DOAJ |
| description | Background & Objectives: The incidence of gestational hypertension is increasing in India which accounts for various maternal morbidity & mortality. As gestational hypertension is hypercogulability state we wanted to assess platelet volume indices in gestational hypertension. Materials and Methods: This is a cross-sectional, case-control study conducted in the Department of Physiology, in collaboration with OBG and Pathology after obtaining institutional ethical clearance. Study includes 60 (n=60) hypertensive as cases and 60 (n=60) normotensive as controls who were in third trimester of pregnancy. Blood pressure was measured using mercury sphygmomanometer and those who had BP values more than 140/90 mmHg without proteinuria were taken as cases and those with normal values were taken as controls. Platelet volume indices were measured using sysmex automated flow meter. Statistically analyzed using t test and pearson’s correlation by SPSS 20 software. Results: Mean platelet volume, platelet distribution width and large cell platelet ratio were higher in hypertensive pregnant female when compared to normotensives which is not statistically significant. (10.72± 1.08 Vs 10.61±1.08 p= 0.56, 12.69± 2.79 Vs 12.57±2.85 p= 0.80, 30.75± 8.50 Vs 29.75±8.70 p= 0.52) plateletcrit was lower in hypertensive when compared to normotensive. (0.23± 0.08 Vs 0.24±0.04 p=0.48) there was no statistical significant correlation exists between BP and platelet volume indices. Conclusion: Our study concludes no strong association of platelet volume indices with severity of hypertension amongst gestational hypertension. |
| first_indexed | 2024-04-10T23:31:45Z |
| format | Article |
| id | doaj.art-6d4607f28bac41bfa16007f06e378b59 |
| institution | Directory Open Access Journal |
| issn | 0974-1143 |
| language | English |
| last_indexed | 2024-04-10T23:31:45Z |
| publishDate | 2023-01-01 |
| publisher | Al Ameen Medical College |
| record_format | Article |
| series | Al Ameen Journal of Medical Sciences |
| spelling | doaj.art-6d4607f28bac41bfa16007f06e378b592023-01-12T05:16:03ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432023-01-0116011217Platelet volume indices in gestational hypertension: An observational studyNagalakshmi Vijaykumar0Deepti Dixit1Sanjivani S. Jadhav2Asha Neravi3Usha Kiran Naidu4Rishab Patil5Department of Physiology, SDM College of Medical Sciences and Hospital, Manjushree Nagar, Sattur, Dharwad-580009, Karnataka, IndiaDepartment of Pathology, SDM College of Medical Sciences & Hospital, Manjushree Nagar, Sattur, Dharwad-580009, Karnataka, IndiaDepartment of Physiology, JGMM Medical College, Gabbur Cross, Hubballi-580028, Karnataka, IndiaDepartment of OBG, SDM College of Medical Sciences & Hospital, Manjushree Nagar, Sattur, Dharwad-580009, Karnataka, IndiaDepartment of OBG, SDM College of Medical Sciences & Hospital, Manjushree Nagar, Sattur, Dharwad-580009, Karnataka, IndiaUnder graduate student, SDM College of Medical Sciences & Hospital, Manjushree Nagar, Sattur, Dharwad-580009, Karnataka, IndiaBackground & Objectives: The incidence of gestational hypertension is increasing in India which accounts for various maternal morbidity & mortality. As gestational hypertension is hypercogulability state we wanted to assess platelet volume indices in gestational hypertension. Materials and Methods: This is a cross-sectional, case-control study conducted in the Department of Physiology, in collaboration with OBG and Pathology after obtaining institutional ethical clearance. Study includes 60 (n=60) hypertensive as cases and 60 (n=60) normotensive as controls who were in third trimester of pregnancy. Blood pressure was measured using mercury sphygmomanometer and those who had BP values more than 140/90 mmHg without proteinuria were taken as cases and those with normal values were taken as controls. Platelet volume indices were measured using sysmex automated flow meter. Statistically analyzed using t test and pearson’s correlation by SPSS 20 software. Results: Mean platelet volume, platelet distribution width and large cell platelet ratio were higher in hypertensive pregnant female when compared to normotensives which is not statistically significant. (10.72± 1.08 Vs 10.61±1.08 p= 0.56, 12.69± 2.79 Vs 12.57±2.85 p= 0.80, 30.75± 8.50 Vs 29.75±8.70 p= 0.52) plateletcrit was lower in hypertensive when compared to normotensive. (0.23± 0.08 Vs 0.24±0.04 p=0.48) there was no statistical significant correlation exists between BP and platelet volume indices. Conclusion: Our study concludes no strong association of platelet volume indices with severity of hypertension amongst gestational hypertension.http://ajms.alameenmedical.org/ArticlePDFs/4%20AJMS%20V16.N1.2023%20p%2012-17.pdfpregnancy induced hypertensionplateletcritmean platelet volume |
| spellingShingle | Nagalakshmi Vijaykumar Deepti Dixit Sanjivani S. Jadhav Asha Neravi Usha Kiran Naidu Rishab Patil Platelet volume indices in gestational hypertension: An observational study Al Ameen Journal of Medical Sciences pregnancy induced hypertension plateletcrit mean platelet volume |
| title | Platelet volume indices in gestational hypertension: An observational study |
| title_full | Platelet volume indices in gestational hypertension: An observational study |
| title_fullStr | Platelet volume indices in gestational hypertension: An observational study |
| title_full_unstemmed | Platelet volume indices in gestational hypertension: An observational study |
| title_short | Platelet volume indices in gestational hypertension: An observational study |
| title_sort | platelet volume indices in gestational hypertension an observational study |
| topic | pregnancy induced hypertension plateletcrit mean platelet volume |
| url | http://ajms.alameenmedical.org/ArticlePDFs/4%20AJMS%20V16.N1.2023%20p%2012-17.pdf |
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