Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L.
Background and purpose: Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds. As a member of this genus, Allium affine, which is locally known as “tareh kouhi”, is an endemic plant of middle...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Research in Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=6;spage=723;epage=727;aulast=Vakili |
| _version_ | 1811225434088538112 |
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| author | Narges Vakili Mahsa Esmaeilifallah Masoud Sadeghi Dinani |
| author_facet | Narges Vakili Mahsa Esmaeilifallah Masoud Sadeghi Dinani |
| author_sort | Narges Vakili |
| collection | DOAJ |
| description | Background and purpose: Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds. As a member of this genus, Allium affine, which is locally known as “tareh kouhi”, is an endemic plant of middle Asian countries.
Experimental approach: Bulbs of A. affine were collected and air-dried in the shade. The chloroform-methanol (9:1) extract of the sample was subjected to purification by MPLC and HPLC. Structure elucidation of isolated compounds was done using comprehensive spectroscopic methods including 1D-NMR, 2D-NMR, and MS.
Findings/Results: A steroidal saponin structurally related to parillin and a phenylpropanoid glycoside (coniferin) were isolated and identified from the plant chloroform-methanol extract.
Conclusion and implication: To the best of our knowledge isolation of these potentially medicinal compounds from A. affine was reported for the first time in this study. |
| first_indexed | 2024-04-12T09:07:11Z |
| format | Article |
| id | doaj.art-6d48627603f545ceb48ec8797d04ac03 |
| institution | Directory Open Access Journal |
| issn | 1735-5362 1735-9414 |
| language | English |
| last_indexed | 2024-04-12T09:07:11Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Research in Pharmaceutical Sciences |
| spelling | doaj.art-6d48627603f545ceb48ec8797d04ac032022-12-22T03:39:04ZengWolters Kluwer Medknow PublicationsResearch in Pharmaceutical Sciences1735-53621735-94142022-01-0117672372710.4103/1735-5362.359438Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L.Narges VakiliMahsa EsmaeilifallahMasoud Sadeghi DinaniBackground and purpose: Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds. As a member of this genus, Allium affine, which is locally known as “tareh kouhi”, is an endemic plant of middle Asian countries. Experimental approach: Bulbs of A. affine were collected and air-dried in the shade. The chloroform-methanol (9:1) extract of the sample was subjected to purification by MPLC and HPLC. Structure elucidation of isolated compounds was done using comprehensive spectroscopic methods including 1D-NMR, 2D-NMR, and MS. Findings/Results: A steroidal saponin structurally related to parillin and a phenylpropanoid glycoside (coniferin) were isolated and identified from the plant chloroform-methanol extract. Conclusion and implication: To the best of our knowledge isolation of these potentially medicinal compounds from A. affine was reported for the first time in this study.http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=6;spage=723;epage=727;aulast=Vakiliallium affine ledebstructure elucidationsteroidal saponinphenylpropanoid. |
| spellingShingle | Narges Vakili Mahsa Esmaeilifallah Masoud Sadeghi Dinani Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. Research in Pharmaceutical Sciences allium affine ledeb structure elucidation steroidal saponin phenylpropanoid. |
| title | Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. |
| title_full | Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. |
| title_fullStr | Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. |
| title_full_unstemmed | Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. |
| title_short | Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L. |
| title_sort | isolation and identification of 6 methoxy parillin and coniferin from the bulbs of allium affine l |
| topic | allium affine ledeb structure elucidation steroidal saponin phenylpropanoid. |
| url | http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=6;spage=723;epage=727;aulast=Vakili |
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