TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS
50 children aged from 3 to 67 months with acute intestinal infections receiving antibiotic therapy, were clinically and microbiologically examined using gas-liquid chromatographic test with the measurement of short-chain fatty acids (SCFAs) in coprofiltrates. The influence on the biocenosis is asses...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2017-09-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/307 |
| _version_ | 1826547114515103744 |
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| author | L. N. Mazankova A. A. Korsunsky A. P. Prodeus M. D. Ardatskaya S. G. Perlovskaya |
| author_facet | L. N. Mazankova A. A. Korsunsky A. P. Prodeus M. D. Ardatskaya S. G. Perlovskaya |
| author_sort | L. N. Mazankova |
| collection | DOAJ |
| description | 50 children aged from 3 to 67 months with acute intestinal infections receiving antibiotic therapy, were clinically and microbiologically examined using gas-liquid chromatographic test with the measurement of short-chain fatty acids (SCFAs) in coprofiltrates. The influence on the biocenosis is assessed upon treatment with an-tidiarrhoeal medication Gelatin tannat (Adiarin), which acts by forming a protective film on the surface of intestinal mucosa preventing loss of body fluids and microbial toxins. 20 children in the control group received antibiotics, sorbents, probiotics. The study has proved the clinical effect of Gelatin tannat, resulting in reduction of time to normalization of diarrhea and intoxication for 2 days, and data on the probiotic effect of the drug, similar to that of probiotics in the control group which expands the indications for the use of Gelatin tannat for prevention of antibiotic-associated diarrhea. |
| first_indexed | 2024-04-10T03:25:30Z |
| format | Article |
| id | doaj.art-6d4c5e89acf54284b018b5bef5ce5136 |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2025-03-14T05:44:30Z |
| publishDate | 2017-09-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-6d4c5e89acf54284b018b5bef5ce51362025-03-05T13:50:43ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072017-09-01163414910.22627/2072-8107-2017-16-3-41-49297TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONSL. N. Mazankova0A. A. Korsunsky1A. P. Prodeus2M. D. Ardatskaya3S. G. Perlovskaya4Department of Pediatric Infiectious Diseases, Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian FederationCity Children’s Hospital № 9 named after G.N. Speransky, MoscowRussian National Research Medical University named after N.I. PirogovEducational and Research Medical Center in the Administrative Department of the President of the Russian FederationCity Children’s Hospital № 9 named after G.N. Speransky, Moscow50 children aged from 3 to 67 months with acute intestinal infections receiving antibiotic therapy, were clinically and microbiologically examined using gas-liquid chromatographic test with the measurement of short-chain fatty acids (SCFAs) in coprofiltrates. The influence on the biocenosis is assessed upon treatment with an-tidiarrhoeal medication Gelatin tannat (Adiarin), which acts by forming a protective film on the surface of intestinal mucosa preventing loss of body fluids and microbial toxins. 20 children in the control group received antibiotics, sorbents, probiotics. The study has proved the clinical effect of Gelatin tannat, resulting in reduction of time to normalization of diarrhea and intoxication for 2 days, and data on the probiotic effect of the drug, similar to that of probiotics in the control group which expands the indications for the use of Gelatin tannat for prevention of antibiotic-associated diarrhea.https://detinf.elpub.ru/jour/article/view/307biocenosis-saving therapyantibioticsacute intestinal infections (aii)short-chain fatty acids (scfas)childrengelatin tannat |
| spellingShingle | L. N. Mazankova A. A. Korsunsky A. P. Prodeus M. D. Ardatskaya S. G. Perlovskaya TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS Детские инфекции (Москва) biocenosis-saving therapy antibiotics acute intestinal infections (aii) short-chain fatty acids (scfas) children gelatin tannat |
| title | TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS |
| title_full | TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS |
| title_fullStr | TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS |
| title_full_unstemmed | TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS |
| title_short | TACTICS OF BIOCENOSIS-SAVING THERAPY BY USE ANTIBIOTICS IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS |
| title_sort | tactics of biocenosis saving therapy by use antibiotics in children with acute intestinal infections |
| topic | biocenosis-saving therapy antibiotics acute intestinal infections (aii) short-chain fatty acids (scfas) children gelatin tannat |
| url | https://detinf.elpub.ru/jour/article/view/307 |
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