Pro-necrotic molecules impact local immunosurveillance in human breast cancer

Pro-necrotic molecules impact local immunosurveillance in human breast cancer

Necrosis culminates in spilling cellular content through the permeabilized plasma membrane, thereby releasing potentially immunostimulatory molecules in the pericellular space of dead cells. Accordingly, molecules involved in necroptotic signaling, such as receptor-interacting serine/threonine-prote...

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Bibliographic Details
Main Authors: Gautier Stoll, Yuting Ma, Heng Yang, Oliver Kepp, Laurence Zitvogel, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:OncoImmunology
Subjects:
apoptosis
immunogenic cell death
immunosurveillance
necrosis
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1299302

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