FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects

Cancer immunotherapy has been extensively investigated in lymphoma over the last three decades. This new treatment modality is now established as a way to manage and maintain several stages and subtypes of lymphoma. The establishment of this novel therapy has necessitated the development of new imag...

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Main Authors: Akram Al-Ibraheem, Ahmed Saad Abdlkadir, Malik E. Juweid, Kamal Al-Rabi, Mohammad Ma’koseh, Hikmat Abdel-Razeq, Asem Mansour
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/4/1063
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author Akram Al-Ibraheem
Ahmed Saad Abdlkadir
Malik E. Juweid
Kamal Al-Rabi
Mohammad Ma’koseh
Hikmat Abdel-Razeq
Asem Mansour
author_facet Akram Al-Ibraheem
Ahmed Saad Abdlkadir
Malik E. Juweid
Kamal Al-Rabi
Mohammad Ma’koseh
Hikmat Abdel-Razeq
Asem Mansour
author_sort Akram Al-Ibraheem
collection DOAJ
description Cancer immunotherapy has been extensively investigated in lymphoma over the last three decades. This new treatment modality is now established as a way to manage and maintain several stages and subtypes of lymphoma. The establishment of this novel therapy has necessitated the development of new imaging response criteria to evaluate and follow up with cancer patients. Several FDG PET/CT-based response criteria have emerged to address and encompass the various most commonly observed response patterns. Many of the proposed response criteria are currently being used to evaluate and predict responses. The purpose of this review is to address the efficacy and side effects of cancer immunotherapy and to correlate this with the proposed criteria and relevant patterns of FDG PET/CT in lymphoma immunotherapy as applicable. The latest updates and future prospects in lymphoma immunotherapy, as well as PET/CT potentials, will be discussed.
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spelling doaj.art-6d4df7c16cd84cc8bbc9c8582bd9ccdf2023-11-16T19:35:36ZengMDPI AGCancers2072-66942023-02-01154106310.3390/cancers15041063FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future ProspectsAkram Al-Ibraheem0Ahmed Saad Abdlkadir1Malik E. Juweid2Kamal Al-Rabi3Mohammad Ma’koseh4Hikmat Abdel-Razeq5Asem Mansour6Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center, Al-Jubeiha, Amman 11941, JordanDepartment of Nuclear Medicine and PET/CT, King Hussein Cancer Center, Al-Jubeiha, Amman 11941, JordanDepartment of Radiology and Nuclear Medicine, Division of Nuclear Medicine, University of Jordan, Amman 11942, JordanDepartment of Medical Oncology, King Hussein Cancer Center, Amman 11941, JordanDepartment of Medical Oncology, King Hussein Cancer Center, Amman 11941, JordanDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, JordanDepartment of Diagnostic Radiology, King Hussein Cancer Center, Amman 11941, JordanCancer immunotherapy has been extensively investigated in lymphoma over the last three decades. This new treatment modality is now established as a way to manage and maintain several stages and subtypes of lymphoma. The establishment of this novel therapy has necessitated the development of new imaging response criteria to evaluate and follow up with cancer patients. Several FDG PET/CT-based response criteria have emerged to address and encompass the various most commonly observed response patterns. Many of the proposed response criteria are currently being used to evaluate and predict responses. The purpose of this review is to address the efficacy and side effects of cancer immunotherapy and to correlate this with the proposed criteria and relevant patterns of FDG PET/CT in lymphoma immunotherapy as applicable. The latest updates and future prospects in lymphoma immunotherapy, as well as PET/CT potentials, will be discussed.https://www.mdpi.com/2072-6694/15/4/1063immunotherapy 1immunotherapy in lymphoma 2FDG PET/CT 3metabolic PET parameters 4lymphoma immunotherapy response criteria 5immuno-PET 6
spellingShingle Akram Al-Ibraheem
Ahmed Saad Abdlkadir
Malik E. Juweid
Kamal Al-Rabi
Mohammad Ma’koseh
Hikmat Abdel-Razeq
Asem Mansour
FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
Cancers
immunotherapy 1
immunotherapy in lymphoma 2
FDG PET/CT 3
metabolic PET parameters 4
lymphoma immunotherapy response criteria 5
immuno-PET 6
title FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
title_full FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
title_fullStr FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
title_full_unstemmed FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
title_short FDG-PET/CT in the Monitoring of Lymphoma Immunotherapy Response: Current Status and Future Prospects
title_sort fdg pet ct in the monitoring of lymphoma immunotherapy response current status and future prospects
topic immunotherapy 1
immunotherapy in lymphoma 2
FDG PET/CT 3
metabolic PET parameters 4
lymphoma immunotherapy response criteria 5
immuno-PET 6
url https://www.mdpi.com/2072-6694/15/4/1063
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