Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters
(1) Background: This study aimed to determine the risk factors for outbreaks of feline panleukopenia in shelters. (2) Methods: Four shelters (A−D) with 150 cats were included. Fecal samples were analyzed by parvovirus real-time polymerase chain reaction (qPCR), including culture and sequencing of qP...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/14/6/1248 |
| _version_ | 1797481420077137920 |
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| author | Teresa Rehme Katrin Hartmann Uwe Truyen Yury Zablotski Michèle Bergmann |
| author_facet | Teresa Rehme Katrin Hartmann Uwe Truyen Yury Zablotski Michèle Bergmann |
| author_sort | Teresa Rehme |
| collection | DOAJ |
| description | (1) Background: This study aimed to determine the risk factors for outbreaks of feline panleukopenia in shelters. (2) Methods: Four shelters (A−D) with 150 cats were included. Fecal samples were analyzed by parvovirus real-time polymerase chain reaction (qPCR), including culture and sequencing of qPCR-positive samples. Information on cats, husbandry, hygiene, and infection management was evaluated to determine risk factors for feline panleukopenia and parvovirus shedding by logistic regression. (3) Results: Feline panleukopenia occurred in 28.0% (42/150) of cats (0 in shelter D). Shedding was found in 48.7% (73/150) (A: 21/73; B: 29/73; C: 7/73; D: 16/73). Of 73 qPCR-positive fecal samples, 65.8% (48/73) were culture-positive; sequencing revealed feline panleukopenia virus (FPV) isolates in 34/48 samples and vaccine virus isolate in 14/48; canine parvovirus was not detected. Presence of feline panleukopenia was significantly more likely in cats from shelter A (<i>p</i> < 0.05), unvaccinated cats (<i>p</i> < 0.001), and young cats (4 weeks to 2 years; <i>p</i> = 0.008). Parvovirus shedding was significantly more common in young cats (<i>p</i> < 0.001), cats with feline panleukopenia (<i>p</i> = 0.033), and group-housed cats (<i>p</i> = 0.025). (4) Conclusions: Vaccination is the most important measure to reduce the risk of feline panleukopenia in shelters. Risk of parvovirus shedding is especially high in young, group-housed cats. |
| first_indexed | 2024-03-09T22:14:19Z |
| format | Article |
| id | doaj.art-6d4fdcf60a8d4479b24762b77596d859 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T22:14:19Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-6d4fdcf60a8d4479b24762b77596d8592023-11-23T19:26:11ZengMDPI AGViruses1999-49152022-06-01146124810.3390/v14061248Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal SheltersTeresa Rehme0Katrin Hartmann1Uwe Truyen2Yury Zablotski3Michèle Bergmann4Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, GermanyClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, GermanyInstitute of Animal Hygiene and Veterinary Public Health, Veterinary Faculty, University of Leipzig, An den Tierkliniken 1, 04103 Leipzig, GermanyClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, GermanyClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany(1) Background: This study aimed to determine the risk factors for outbreaks of feline panleukopenia in shelters. (2) Methods: Four shelters (A−D) with 150 cats were included. Fecal samples were analyzed by parvovirus real-time polymerase chain reaction (qPCR), including culture and sequencing of qPCR-positive samples. Information on cats, husbandry, hygiene, and infection management was evaluated to determine risk factors for feline panleukopenia and parvovirus shedding by logistic regression. (3) Results: Feline panleukopenia occurred in 28.0% (42/150) of cats (0 in shelter D). Shedding was found in 48.7% (73/150) (A: 21/73; B: 29/73; C: 7/73; D: 16/73). Of 73 qPCR-positive fecal samples, 65.8% (48/73) were culture-positive; sequencing revealed feline panleukopenia virus (FPV) isolates in 34/48 samples and vaccine virus isolate in 14/48; canine parvovirus was not detected. Presence of feline panleukopenia was significantly more likely in cats from shelter A (<i>p</i> < 0.05), unvaccinated cats (<i>p</i> < 0.001), and young cats (4 weeks to 2 years; <i>p</i> = 0.008). Parvovirus shedding was significantly more common in young cats (<i>p</i> < 0.001), cats with feline panleukopenia (<i>p</i> = 0.033), and group-housed cats (<i>p</i> = 0.025). (4) Conclusions: Vaccination is the most important measure to reduce the risk of feline panleukopenia in shelters. Risk of parvovirus shedding is especially high in young, group-housed cats.https://www.mdpi.com/1999-4915/14/6/1248feline panleukopenia virusFPVsheddingshelter managementshelter medicinevaccination |
| spellingShingle | Teresa Rehme Katrin Hartmann Uwe Truyen Yury Zablotski Michèle Bergmann Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters Viruses feline panleukopenia virus FPV shedding shelter management shelter medicine vaccination |
| title | Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters |
| title_full | Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters |
| title_fullStr | Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters |
| title_full_unstemmed | Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters |
| title_short | Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters |
| title_sort | feline panleukopenia outbreaks and risk factors in cats in animal shelters |
| topic | feline panleukopenia virus FPV shedding shelter management shelter medicine vaccination |
| url | https://www.mdpi.com/1999-4915/14/6/1248 |
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