Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection
This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present dat...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-02-01
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| Series: | Data in Brief |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S235234092201054X |
| _version_ | 1797938053338103808 |
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| author | Veronika Leiss Roland P. Piekorz Salvador Castaneda Vega Christoph Jacoby Ulrich Flögel Katja Pexa Jürgen Schrader Bernd J. Pichler Sandra Beer-Hammer Bernd Nürnberg |
| author_facet | Veronika Leiss Roland P. Piekorz Salvador Castaneda Vega Christoph Jacoby Ulrich Flögel Katja Pexa Jürgen Schrader Bernd J. Pichler Sandra Beer-Hammer Bernd Nürnberg |
| author_sort | Veronika Leiss |
| collection | DOAJ |
| description | This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarction and neurological deficits, as well as the consequences of PTX pretreatment on reperfusion after occlusion using time-of-flight magnetic resonance angiography. With these data, we aim to provide detailed experimental settings of this newly described model. |
| first_indexed | 2024-04-10T18:54:42Z |
| format | Article |
| id | doaj.art-6d52e522230f44f88f77be6845265ce5 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-04-10T18:54:42Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-6d52e522230f44f88f77be6845265ce52023-02-01T04:26:30ZengElsevierData in Brief2352-34092023-02-0146108851Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injectionVeronika Leiss0Roland P. Piekorz1Salvador Castaneda Vega2Christoph Jacoby3Ulrich Flögel4Katja Pexa5Jürgen Schrader6Bernd J. Pichler7Sandra Beer-Hammer8Bernd Nürnberg9Department of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, GermanyInstitute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Department of Nuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University Tübingen and University Clinic, Tübingen, GermanyInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyInstitute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, GermanyWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University, Tübingen, GermanyDepartment of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University, Tübingen, Germany; Corresponding author.Department of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, GermanyThis article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarction and neurological deficits, as well as the consequences of PTX pretreatment on reperfusion after occlusion using time-of-flight magnetic resonance angiography. With these data, we aim to provide detailed experimental settings of this newly described model.http://www.sciencedirect.com/science/article/pii/S235234092201054XAngiographyGi proteinsischemic strokemurine model |
| spellingShingle | Veronika Leiss Roland P. Piekorz Salvador Castaneda Vega Christoph Jacoby Ulrich Flögel Katja Pexa Jürgen Schrader Bernd J. Pichler Sandra Beer-Hammer Bernd Nürnberg Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection Data in Brief Angiography Gi proteins ischemic stroke murine model |
| title | Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection |
| title_full | Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection |
| title_fullStr | Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection |
| title_full_unstemmed | Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection |
| title_short | Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection |
| title_sort | data on common carotid artery occlusion inducing focalized stroke lesions after pertussis toxin injection |
| topic | Angiography Gi proteins ischemic stroke murine model |
| url | http://www.sciencedirect.com/science/article/pii/S235234092201054X |
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