Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton

Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton

Abstract Background PPFIA1 is located at the 11q13 region commonly amplified in cancer. The protein liprin-α1 encoded by PPF1A1 contributes to the adhesive and invasive structures of cytoskeletal elements and is located at the invadosomes in cancer cells. However, the precise mechanism of liprin-α1...

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Bibliographic Details
Main Authors: Henna Pehkonen, Mira Lento, Pernilla von Nandelstadh, Artemis Filippou, Reidar Grénman, Kaisa Lehti, Outi Monni
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cell Communication and Signaling
Subjects:
Liprin-α1
PPFIA1
CD82
Head and neck cancer
Breast cancer
Invasion
Online Access:http://link.springer.com/article/10.1186/s12964-018-0253-y

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http://link.springer.com/article/10.1186/s12964-018-0253-y

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