PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53

Abstract Colorectal cancer is the most common gastrointestinal cancer and causes severe damage to human health. PRDX2 is a member of the peroxiredoxin family reported to have a high level of expression in colorectal cancer. However, the mechanisms by which PRDX2 promotes the proliferation of colorec...

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Bibliographic Details
Main Authors: Wuyi Wang, Jinlai Wei, Hairong Zhang, Xiangru Zheng, He Zhou, Yajun Luo, Jianguo Yang, Qican Deng, Siqi Huang, Zhongxue Fu
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03888-1