miRNA regulatory circuits in ES cells differentiation: a chemical kinetics modeling approach.

miRNA regulatory circuits in ES cells differentiation: a chemical kinetics modeling approach.

MicroRNAs (miRNAs) play an important role in gene regulation for Embryonic Stem cells (ES cells), where they either down-regulate target mRNA genes by degradation or repress protein expression of these mRNA genes by inhibiting translation. Well known tables TargetScan and miRanda may predict quite l...

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Bibliographic Details
Main Authors: Zijun Luo, Xuping Xu, Peili Gu, David Lonard, Preethi H Gunaratne, Austin J Cooney, Robert Azencott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3198445?pdf=render

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