A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

RIG-I-like receptor (RLR) plays a pivotal role in the detection of invading pathogens to initiate type I interferon (IFN) gene transcription. Since aberrant IFN production is harmful, RLR signaling is strictly regulated. However, the regulatory mechanisms are not fully understood. By expression clon...

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Bibliographic Details
Main Authors: Ryo Narita, Kiyohiro Takahasi, Etsu Murakami, Emi Hirano, Seiji P Yamamoto, Mitsutoshi Yoneyama, Hiroki Kato, Takashi Fujita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4207803?pdf=render

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http://europepmc.org/articles/PMC4207803?pdf=render

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