Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice

Background: Since the first human infection with H9N2 virus was reported in 1998, the number of cases of H9N2 infection has exceeded one hundred by 2021. However, there is no systematic description of the biological characteristics of H9N2 viruses isolated from humans. Methods: Therefore, this study...

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Bibliographic Details
Main Authors: Min Tan, Ye Zhang, Hong Bo, Xiyan Li, Shumei Zou, Lei Yang, Jia Liu, Qi Chen, Xiaohao Xu, Wenfei Zhu, Dayan Wang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Infectious Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772431X24000042