Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study

Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study

Background: Methodological challenges limit the use of brain atrophy and lesion burden measures in the follow-up of multiple sclerosis (MS) patients on clinical routine datasets. Objective: To determine the feasibility of T2-FLAIR-only measures of lateral ventricular volume (LVV) and salient central...

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Bibliographic Details
Main Authors: Michael Barnett, Niels Bergsland, Bianca Weinstock-Guttman, Helmut Butzkueven, Tomas Kalincik, Patricia Desmond, Frank Gaillard, Vincent van Pesch, Serkan Ozakbas, Juan Ignacio Rojas, Cavit Boz, Ayse Altintas, Chenyu Wang, Michael G. Dwyer, Suzie Yang, Dejan Jakimovski, Kain Kyle, Deepa P. Ramasamy, Robert Zivadinov
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Multiple sclerosis
Disability progression
Brain atrophy
Lateral ventricle volume
Lesion burden
Salient central lesion volume
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158221002461

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