Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19

Background: As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. Objective: Utilising the Spectrum GOALS module (GOALS-2021), the 5-year outcomes from the impleme...

Full description

Bibliographic Details
Main Authors: Keith Jefferis, Ava Avalos, Heston Phillips, Mpho Mmelesi, Dinah Ramaabya, Bornapate Nkomo, Charles Muthoga, Joseph N. Jarvis, Siphiwe Ratladi, Robert Selato, John Stover
Format: Article
Language:English
Published: AOSIS 2021-10-01
Series:Southern African Journal of HIV Medicine
Subjects:
Online Access:https://sajhivmed.org.za/index.php/hivmed/article/view/1275
_version_ 1818140642344173568
author Keith Jefferis
Ava Avalos
Heston Phillips
Mpho Mmelesi
Dinah Ramaabya
Bornapate Nkomo
Charles Muthoga
Joseph N. Jarvis
Siphiwe Ratladi
Robert Selato
John Stover
author_facet Keith Jefferis
Ava Avalos
Heston Phillips
Mpho Mmelesi
Dinah Ramaabya
Bornapate Nkomo
Charles Muthoga
Joseph N. Jarvis
Siphiwe Ratladi
Robert Selato
John Stover
author_sort Keith Jefferis
collection DOAJ
description Background: As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. Objective: Utilising the Spectrum GOALS module (GOALS-2021), the 5-year outcomes from the implementation of the Treat All strategy were analysed and compared with the original 2016 Investment Case (2016-IC) projections. Future impact of adopting the new Joint United Nations Programme on HIV/AIDS (UNAIDS) Global AIDS Strategy (2021–2026) targets and macroeconomic analysis estimating how the financial constraints from the COVID-19 pandemic could impact the available resources for Botswana’s National HIV Response through 2030 were also considered. Method: Programmatic costs, population demographics, prevention and treatment outputs were determined. Previous 2016-IC data were uploaded for comparison, and inputs for the GOALS, AIM, DemProj, Resource Needs and Family Planning modules were derived from published reports, strategic plans, programmatic data and expert opinion. The economic projections were recalibrated with consideration of the impact of the COVID-19 pandemic. Results: Decreases in HIV infections, incidence and mortality rates were achieved. Increases in laboratory costs were offset by estimated decreases in the population of people living with HIV (PLWH). Moving forward, young women and others at high risk must be targeted in HIV prevention efforts, as Botswana transitions from a generalised to a more concentrated epidemic. Conclusion: The Treat All strategy contributed positively to decreases in new HIV infections, mortality and costs. If significant improvements in differentiated service delivery, increases in human resources and HIV prevention can be realised, Botswana could become one of the first countries with a previously high-burdened generalised HIV epidemic to gain epidemic control, despite the demands of the COVID-19 pandemic.
first_indexed 2024-12-11T10:47:14Z
format Article
id doaj.art-6d65c8eb644048febc7085b793d49f0e
institution Directory Open Access Journal
issn 1608-9693
2078-6751
language English
last_indexed 2024-12-11T10:47:14Z
publishDate 2021-10-01
publisher AOSIS
record_format Article
series Southern African Journal of HIV Medicine
spelling doaj.art-6d65c8eb644048febc7085b793d49f0e2022-12-22T01:10:26ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512021-10-01221e1e1110.4102/sajhivmed.v22i1.1275773Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19Keith Jefferis0Ava Avalos1Heston Phillips2Mpho Mmelesi3Dinah Ramaabya4Bornapate Nkomo5Charles Muthoga6Joseph N. Jarvis7Siphiwe Ratladi8Robert Selato9John Stover10E-consult Botswana, GaboroneCareena Centre for Health, GaboroneUNAIDS, LusakaUNAIDS, GaboroneBotswana Ministry of Health and Wellness, GaboroneBotswana Ministry of Health and Wellness, GaboroneBotswana Harvard AIDS Institute Partnership, GaboroneBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana; and, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, LondonNational AIDS and Public Health Agency, GaboroneNational AIDS and Public Health Agency, GaboroneAvenir Health, Glastonbury, United States of AmericaBackground: As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. Objective: Utilising the Spectrum GOALS module (GOALS-2021), the 5-year outcomes from the implementation of the Treat All strategy were analysed and compared with the original 2016 Investment Case (2016-IC) projections. Future impact of adopting the new Joint United Nations Programme on HIV/AIDS (UNAIDS) Global AIDS Strategy (2021–2026) targets and macroeconomic analysis estimating how the financial constraints from the COVID-19 pandemic could impact the available resources for Botswana’s National HIV Response through 2030 were also considered. Method: Programmatic costs, population demographics, prevention and treatment outputs were determined. Previous 2016-IC data were uploaded for comparison, and inputs for the GOALS, AIM, DemProj, Resource Needs and Family Planning modules were derived from published reports, strategic plans, programmatic data and expert opinion. The economic projections were recalibrated with consideration of the impact of the COVID-19 pandemic. Results: Decreases in HIV infections, incidence and mortality rates were achieved. Increases in laboratory costs were offset by estimated decreases in the population of people living with HIV (PLWH). Moving forward, young women and others at high risk must be targeted in HIV prevention efforts, as Botswana transitions from a generalised to a more concentrated epidemic. Conclusion: The Treat All strategy contributed positively to decreases in new HIV infections, mortality and costs. If significant improvements in differentiated service delivery, increases in human resources and HIV prevention can be realised, Botswana could become one of the first countries with a previously high-burdened generalised HIV epidemic to gain epidemic control, despite the demands of the COVID-19 pandemic.https://sajhivmed.org.za/index.php/hivmed/article/view/1275botswanaspectrumgoalseconomic modellingcovid-19treat all
spellingShingle Keith Jefferis
Ava Avalos
Heston Phillips
Mpho Mmelesi
Dinah Ramaabya
Bornapate Nkomo
Charles Muthoga
Joseph N. Jarvis
Siphiwe Ratladi
Robert Selato
John Stover
Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
Southern African Journal of HIV Medicine
botswana
spectrum
goals
economic modelling
covid-19
treat all
title Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
title_full Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
title_fullStr Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
title_full_unstemmed Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
title_short Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19
title_sort five years after treat all implementation botswana s hiv response and future directions in the era of covid 19
topic botswana
spectrum
goals
economic modelling
covid-19
treat all
url https://sajhivmed.org.za/index.php/hivmed/article/view/1275
work_keys_str_mv AT keithjefferis fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT avaavalos fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT hestonphillips fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT mphommelesi fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT dinahramaabya fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT bornapatenkomo fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT charlesmuthoga fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT josephnjarvis fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT siphiweratladi fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT robertselato fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19
AT johnstover fiveyearsaftertreatallimplementationbotswanashivresponseandfuturedirectionsintheeraofcovid19