Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators
Activation of nuclear factor erythroid-2-related factor 2 (NRF2) has been proven to be an effective means to prevent the development of cancer, and natural curcumin stands out as a potent NRF2 activator and cancer chemopreventive agent. In this study, we have synthesized a series of 4-anilinoquinoli...
Main Authors: | Yu-Tse Kao, Yi-Siao Chen, Kai-Wei Tang, Jin-Ching Lee, Chih-Hua Tseng, Cherng-Chyi Tzeng, Chia-Hung Yen, Yeh-Long Chen |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/14/3133 |
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