mTORC2 Regulates Cardiac Response to Stress by Inhibiting MST1
The mTOR and Hippo pathways have recently emerged as the major signaling transduction cascades regulating organ size and cellular homeostasis. However, direct crosstalk between two pathways is yet to be determined. Here, we demonstrate that mTORC2 is a direct negative regulator of the MST1 kinase, a...
Main Authors: | Sebastiano Sciarretta, Peiyong Zhai, Yasuhiro Maejima, Dominic P. Del Re, Narayani Nagarajan, Derek Yee, Tong Liu, Mark A. Magnuson, Massimo Volpe, Giacomo Frati, Hong Li, Junichi Sadoshima |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715002636 |
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