The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood cancer that comprises 10−15% of pediatric and ~25% of adult ALL cases. Although the curative rates have significantly improved over the past 10 years, especially in pediatric patients, T-ALL remains a challenge from a thera...

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Bibliographic Details
Main Authors: Alberto M. Martelli, Francesca Paganelli, Antonietta Fazio, Chiara Bazzichetto, Fabiana Conciatori, James A. McCubrey
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/5/629

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