The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood cancer that comprises 10−15% of pediatric and ~25% of adult ALL cases. Although the curative rates have significantly improved over the past 10 years, especially in pediatric patients, T-ALL remains a challenge from a thera...
Main Authors: | Alberto M. Martelli, Francesca Paganelli, Antonietta Fazio, Chiara Bazzichetto, Fabiana Conciatori, James A. McCubrey |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/5/629 |
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