The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA

The Vaccine Safety Datalink is a collaborative project involving the National Immunization Program of the Centers for Disease Control and Prevention and several large health maintenance organizations in the USA. The project began in 1990 with the primary purpose of rigorously evaluating concerns abo...

Full description

Bibliographic Details
Main Authors: R.T. Chen, F. DeStefano, R.L. Davis, L.A. Jackson, R.S. Thompson, J.P. Mullooly, S.B. Black, H.R. Shinefield, C.M. Vadheim, J.I. Ward, S.M. Marcy
Format: Article
Language:English
Published: The World Health Organization
Series:Bulletin of the World Health Organization
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862000000200006&lng=en&tlng=en
_version_ 1797288970941366272
author R.T. Chen
F. DeStefano
R.L. Davis
L.A. Jackson
R.S. Thompson
J.P. Mullooly
S.B. Black
H.R. Shinefield
C.M. Vadheim
J.I. Ward
S.M. Marcy
author_facet R.T. Chen
F. DeStefano
R.L. Davis
L.A. Jackson
R.S. Thompson
J.P. Mullooly
S.B. Black
H.R. Shinefield
C.M. Vadheim
J.I. Ward
S.M. Marcy
author_sort R.T. Chen
collection DOAJ
description The Vaccine Safety Datalink is a collaborative project involving the National Immunization Program of the Centers for Disease Control and Prevention and several large health maintenance organizations in the USA. The project began in 1990 with the primary purpose of rigorously evaluating concerns about the safety of vaccines. Computerized data on vaccination, medical outcome (e.g. outpatient visits, emergency room visits, hospitalizations, and deaths) and covariates (e.g. birth certificates, census data) are prospectively collected and linked under joint protocol at multiple health maintenance organizations for analysis. Approximately 6 million persons (2% of the population of the USA) are now members of health maintenance organizations participating in the Vaccine Safety Datalink, which has proved to be a valuable resource providing important information on a number of vaccine safety issues. The databases and infrastructure created for the Vaccine Safety Datalink have also provided opportunities to address vaccination coverage, cost-effectiveness and other matters connected with immunization as well as matters outside this field.
first_indexed 2024-03-07T18:57:23Z
format Article
id doaj.art-6d6e6de40c5f4c6388df4e9e7bc342d2
institution Directory Open Access Journal
issn 0042-9686
language English
last_indexed 2024-03-07T18:57:23Z
publisher The World Health Organization
record_format Article
series Bulletin of the World Health Organization
spelling doaj.art-6d6e6de40c5f4c6388df4e9e7bc342d22024-03-02T00:10:04ZengThe World Health OrganizationBulletin of the World Health Organization0042-968678218619410.1590/S0042-96862000000200006S0042-96862000000200006The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USAR.T. Chen0F. DeStefano1R.L. Davis2L.A. Jackson3R.S. Thompson4J.P. Mullooly5S.B. Black6H.R. Shinefield7C.M. Vadheim8J.I. Ward9S.M. Marcy10Centers for Disease Control and PreventionCenters for Disease Control and PreventionGroup Health Cooperative of Puget SoundGroup Health Cooperative of Puget SoundGroup Health Cooperative of Puget SoundNorthwest Kaiser PermanenteNorthern California Kaiser PermanenteNorthern California Kaiser PermanenteHarbor-UCLA Medical CenterHarbor-UCLA Medical CenterSouthern California Kaiser PermanenteThe Vaccine Safety Datalink is a collaborative project involving the National Immunization Program of the Centers for Disease Control and Prevention and several large health maintenance organizations in the USA. The project began in 1990 with the primary purpose of rigorously evaluating concerns about the safety of vaccines. Computerized data on vaccination, medical outcome (e.g. outpatient visits, emergency room visits, hospitalizations, and deaths) and covariates (e.g. birth certificates, census data) are prospectively collected and linked under joint protocol at multiple health maintenance organizations for analysis. Approximately 6 million persons (2% of the population of the USA) are now members of health maintenance organizations participating in the Vaccine Safety Datalink, which has proved to be a valuable resource providing important information on a number of vaccine safety issues. The databases and infrastructure created for the Vaccine Safety Datalink have also provided opportunities to address vaccination coverage, cost-effectiveness and other matters connected with immunization as well as matters outside this field.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862000000200006&lng=en&tlng=enadverse drug reaction reporting systemshealth maintenance organizationsvaccines, combined, adverse effectsviral vaccines, adverse effectsUnited States
spellingShingle R.T. Chen
F. DeStefano
R.L. Davis
L.A. Jackson
R.S. Thompson
J.P. Mullooly
S.B. Black
H.R. Shinefield
C.M. Vadheim
J.I. Ward
S.M. Marcy
The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
Bulletin of the World Health Organization
adverse drug reaction reporting systems
health maintenance organizations
vaccines, combined, adverse effects
viral vaccines, adverse effects
United States
title The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
title_full The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
title_fullStr The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
title_full_unstemmed The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
title_short The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
title_sort vaccine safety datalink immunization research in health maintenance organizations in the usa
topic adverse drug reaction reporting systems
health maintenance organizations
vaccines, combined, adverse effects
viral vaccines, adverse effects
United States
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862000000200006&lng=en&tlng=en
work_keys_str_mv AT rtchen thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT fdestefano thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT rldavis thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT lajackson thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT rsthompson thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT jpmullooly thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT sbblack thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT hrshinefield thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT cmvadheim thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT jiward thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT smmarcy thevaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT rtchen vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT fdestefano vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT rldavis vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT lajackson vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT rsthompson vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT jpmullooly vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT sbblack vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT hrshinefield vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT cmvadheim vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT jiward vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa
AT smmarcy vaccinesafetydatalinkimmunizationresearchinhealthmaintenanceorganizationsintheusa