Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series

Abstract Background Spontaneous Coronary Artery Dissection (SCAD) and Takotsubo Syndrome (TTS) are two different entities with several shared risk factors, but their management is different. They can co-exist in patients with chest pain which affects their management. We present two cases of combine...

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Main Authors: Saadat Ali Saleemi, Lung En Teng, Ronald J. L. Dick
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:The Egyptian Heart Journal
Subjects:
Online Access:https://doi.org/10.1186/s43044-023-00361-6
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author Saadat Ali Saleemi
Lung En Teng
Ronald J. L. Dick
author_facet Saadat Ali Saleemi
Lung En Teng
Ronald J. L. Dick
author_sort Saadat Ali Saleemi
collection DOAJ
description Abstract Background Spontaneous Coronary Artery Dissection (SCAD) and Takotsubo Syndrome (TTS) are two different entities with several shared risk factors, but their management is different. They can co-exist in patients with chest pain which affects their management. We present two cases of combined SCAD and TTS in patients presented with chest pain. Case presentation Case 1: 80F admitted with typical chest pain and dynamic ECG changes on the background of known anxiety/depression and social stresses. Her coronary angiogram showed SCAD affecting distal LAD. The left ventriculogram (LV gram) showed apical ballooning consistent with Takotsubo Syndrome (TTS). Patient was discharged on aspirin as well as angiotensin receptor blocker (ARB). Case 2: 60F admitted with typical chest pain in the setting of emotional trauma on the background of known cardiovascular risk factors. She was found to have ST elevation in inferior leads with no reciprocal changes. Subsequently, coronary angiogram showed SCAD affecting mid-left anterior descending artery (LAD) with normal distal wrap around LAD. Her LV gram showed apical ballooning consistent with TTS. However, transthoracic echocardiogram showed akinetic left ventricular apex. She was discharged on aspirin as well as an ACE inhibitor and warfarin to prevent LV thrombus. Conclusions SCAD and TTS can co-exist in patients with chest pain. It is important to identify SCAD in patients with TTS as it may affect their short as well as long-term management.
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spelling doaj.art-6d6eeb88b35d4cb6b4c508ab1869edf82023-04-30T11:19:41ZengSpringerOpenThe Egyptian Heart Journal2090-911X2023-04-017511810.1186/s43044-023-00361-6Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case seriesSaadat Ali Saleemi0Lung En Teng1Ronald J. L. Dick2Department of CardiologyDepartment of General Medicine, Peninsula HealthDepartment of CardiologyAbstract Background Spontaneous Coronary Artery Dissection (SCAD) and Takotsubo Syndrome (TTS) are two different entities with several shared risk factors, but their management is different. They can co-exist in patients with chest pain which affects their management. We present two cases of combined SCAD and TTS in patients presented with chest pain. Case presentation Case 1: 80F admitted with typical chest pain and dynamic ECG changes on the background of known anxiety/depression and social stresses. Her coronary angiogram showed SCAD affecting distal LAD. The left ventriculogram (LV gram) showed apical ballooning consistent with Takotsubo Syndrome (TTS). Patient was discharged on aspirin as well as angiotensin receptor blocker (ARB). Case 2: 60F admitted with typical chest pain in the setting of emotional trauma on the background of known cardiovascular risk factors. She was found to have ST elevation in inferior leads with no reciprocal changes. Subsequently, coronary angiogram showed SCAD affecting mid-left anterior descending artery (LAD) with normal distal wrap around LAD. Her LV gram showed apical ballooning consistent with TTS. However, transthoracic echocardiogram showed akinetic left ventricular apex. She was discharged on aspirin as well as an ACE inhibitor and warfarin to prevent LV thrombus. Conclusions SCAD and TTS can co-exist in patients with chest pain. It is important to identify SCAD in patients with TTS as it may affect their short as well as long-term management.https://doi.org/10.1186/s43044-023-00361-6SCADTTSCardiovascularNSTEMICardiomyopathy
spellingShingle Saadat Ali Saleemi
Lung En Teng
Ronald J. L. Dick
Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
The Egyptian Heart Journal
SCAD
TTS
Cardiovascular
NSTEMI
Cardiomyopathy
title Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
title_full Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
title_fullStr Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
title_full_unstemmed Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
title_short Combined spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS): a case series
title_sort combined spontaneous coronary artery dissection scad and takotsubo syndrome tts a case series
topic SCAD
TTS
Cardiovascular
NSTEMI
Cardiomyopathy
url https://doi.org/10.1186/s43044-023-00361-6
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