Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment

Objective To propose and test the validity of a new syndrome called retrograde cricopharyngeus dysfunction (R-CPD) that explains inability to belch and the associated symptoms of loud gurgling noises, chest and abdominal pain/distention, and excessive flatulence, as well as to report the results of...

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Main Authors: Robert W. Bastian MD, Melissa L. Smithson MS, PA-C
Format: Article
Language:English
Published: Wiley 2019-03-01
Series:OTO Open
Online Access:https://doi.org/10.1177/2473974X19834553
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author Robert W. Bastian MD
Melissa L. Smithson MS, PA-C
author_facet Robert W. Bastian MD
Melissa L. Smithson MS, PA-C
author_sort Robert W. Bastian MD
collection DOAJ
description Objective To propose and test the validity of a new syndrome called retrograde cricopharyngeus dysfunction (R-CPD) that explains inability to belch and the associated symptoms of loud gurgling noises, chest and abdominal pain/distention, and excessive flatulence, as well as to report the results of botulinum toxin (BT) injection into the cricopharyngeus muscle (CPM) for both diagnosis and treatment of R-CPD. Study Design To develop a case series of consecutive patients matched to the syndromic features of R-CPD, inject the CPM with BT as a concurrent diagnostic and therapeutic maneuver, and assess results. Setting Bastian Voice Institute (Downers Grove, Illinois). Subjects and Methods Consecutive (unselected) patients presenting with inability to belch and associated symptoms were matched to the proposed syndrome of R-CPD, treated with BT, and followed for effect on symptoms over time. Results All 51 patients achieved ability to belch and relief of associated symptoms, and the majority seem to have “retrained” the ability to belch on a potentially “permanent” basis. Conclusion R-CPD can be diagnosed syndromically, using a symptom complex; clinical diagnosis is validated by relief of symptoms after BT injection; and BT into the CPM is an efficacious treatment, whose benefit appears to often last longer than the pharmacologic duration of action of BT.
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spelling doaj.art-6d702f90c1264051b0cf1e3a7213cdec2023-12-03T00:13:55ZengWileyOTO Open2473-974X2019-03-01310.1177/2473974X19834553Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and TreatmentRobert W. Bastian MD0Melissa L. Smithson MS, PA-C1Bastian Voice Institute, Downers Grove, Illinois, USABastian Voice Institute, Downers Grove, Illinois, USAObjective To propose and test the validity of a new syndrome called retrograde cricopharyngeus dysfunction (R-CPD) that explains inability to belch and the associated symptoms of loud gurgling noises, chest and abdominal pain/distention, and excessive flatulence, as well as to report the results of botulinum toxin (BT) injection into the cricopharyngeus muscle (CPM) for both diagnosis and treatment of R-CPD. Study Design To develop a case series of consecutive patients matched to the syndromic features of R-CPD, inject the CPM with BT as a concurrent diagnostic and therapeutic maneuver, and assess results. Setting Bastian Voice Institute (Downers Grove, Illinois). Subjects and Methods Consecutive (unselected) patients presenting with inability to belch and associated symptoms were matched to the proposed syndrome of R-CPD, treated with BT, and followed for effect on symptoms over time. Results All 51 patients achieved ability to belch and relief of associated symptoms, and the majority seem to have “retrained” the ability to belch on a potentially “permanent” basis. Conclusion R-CPD can be diagnosed syndromically, using a symptom complex; clinical diagnosis is validated by relief of symptoms after BT injection; and BT into the CPM is an efficacious treatment, whose benefit appears to often last longer than the pharmacologic duration of action of BT.https://doi.org/10.1177/2473974X19834553
spellingShingle Robert W. Bastian MD
Melissa L. Smithson MS, PA-C
Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
OTO Open
title Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
title_full Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
title_fullStr Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
title_full_unstemmed Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
title_short Inability to Belch and Associated Symptoms Due to Retrograde Cricopharyngeus Dysfunction: Diagnosis and Treatment
title_sort inability to belch and associated symptoms due to retrograde cricopharyngeus dysfunction diagnosis and treatment
url https://doi.org/10.1177/2473974X19834553
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