Donor-specific Anti-HLA antibodies in allogeneic hematopoietic stem cell transplantation

Donor-specific Anti-HLA antibodies in allogeneic hematopoietic stem cell transplantation

Allogeneic Hematopoietic Stem Cell Transplantation (AHSCT) is a curative treatment for a wide variety of hematological diseases. In 30% of the cases, a geno-identical donor is available. Any other situation displays some level of Human Leukocyte Antigen (HLA) incompatibility between donor and recipi...

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Bibliographic Details
Main Authors: Sarah Morin-Zorman, Pascale Loiseau, Jean-Luc Taupin, Sophie Caillat-Zucman
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Immunology
Subjects:
HLA Antigens
allogeneic hematopoietic stem cell transplantation
donor-specific antibodies
Graft failure
Single antigen flow bead assay
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00307/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00307/full

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