DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites

DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites

Abstract Background We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver metastasis and intrahepatic cholangiocarcinoma (iCCA) with high accuracy (PAAD-iCCA-Classifier). PAAD is one of the leading causes of cancer of un...

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Bibliographic Details
Main Authors: Teodor G. Calina, Eilís Perez, Elena Grafenhorst, Jamal Benhamida, Simon Schallenberg, Adrian Popescu, Ines Koch, Tobias Janik, BaoQing Chen, Jana Ihlow, Stephanie Roessler, Benjamin Goeppert, Bruno Sinn, Marcus Bahra, George A. Calin, Eliane T. Taube, Uwe Pelzer, Christopher C. M. Neumann, David Horst, Erik Knutsen, David Capper, Mihnea P. Dragomir
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Clinical Epigenetics
Subjects:
Pancreatic ductal adenocarcinoma
DNA methylation
Molecular diagnosis
Cancer of unknown primary
Epigenetics
Online Access:https://doi.org/10.1186/s13148-024-01768-x

Internet

https://doi.org/10.1186/s13148-024-01768-x

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