Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario
Abstract Background Renal metastasis is a rare manifestation of germ cell tumors. Extension of malignant lesions into the renal vein can complicate the scenario. Case This report presents a 35‐year‐old man with primary stage IS NSGCT. Fourteen months after radical orchiectomy he presented with metas...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-12-01
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| Series: | Cancer Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cnr2.1910 |
| _version_ | 1827372820372389888 |
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| author | Hamidreza Ghorbani Ali Emadi Torghabeh Mahdi Farzadnia Alireza Golshan Parisa Rabiei |
| author_facet | Hamidreza Ghorbani Ali Emadi Torghabeh Mahdi Farzadnia Alireza Golshan Parisa Rabiei |
| author_sort | Hamidreza Ghorbani |
| collection | DOAJ |
| description | Abstract Background Renal metastasis is a rare manifestation of germ cell tumors. Extension of malignant lesions into the renal vein can complicate the scenario. Case This report presents a 35‐year‐old man with primary stage IS NSGCT. Fourteen months after radical orchiectomy he presented with metastasis in the lung, kidney, and para‐aortic lymph nodes. He received multiple lines of salvage treatments including chemotherapy and surgery. Intraoperative exploration during radical nephrectomy and retroperitoneal lymphadenectomy revealed intra‐renal vein involvement with a prominent teratomatous component. Conclusion Defining the exact extent of malignant lesions, especially endovascular lesions, is very important to clarify how advanced the malignant lesions are. The surgeons must be aware of the risk factors that predict vascular involvement, and therefore, providing intraoperative access to vascular surgery procedures when needed. |
| first_indexed | 2024-03-08T11:06:20Z |
| format | Article |
| id | doaj.art-6d74c577ff9346acb1b3f5d949a52cd9 |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-03-08T11:06:20Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-6d74c577ff9346acb1b3f5d949a52cd92024-01-26T14:41:21ZengWileyCancer Reports2573-83482023-12-01612n/an/a10.1002/cnr2.1910Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenarioHamidreza Ghorbani0Ali Emadi Torghabeh1Mahdi Farzadnia2Alireza Golshan3Parisa Rabiei4Kidney Transplantation Complications Research Center Mashhad University of Medical Sciences Mashhad IranCancer Research Center Mashhad University of Medical Sciences Mashhad IranDepartment of Pathology Mashhad University of Medical Sciences Mashhad IranKidney Transplantation Complications Research Center Mashhad University of Medical Sciences Mashhad IranCancer Research Center Mashhad University of Medical Sciences Mashhad IranAbstract Background Renal metastasis is a rare manifestation of germ cell tumors. Extension of malignant lesions into the renal vein can complicate the scenario. Case This report presents a 35‐year‐old man with primary stage IS NSGCT. Fourteen months after radical orchiectomy he presented with metastasis in the lung, kidney, and para‐aortic lymph nodes. He received multiple lines of salvage treatments including chemotherapy and surgery. Intraoperative exploration during radical nephrectomy and retroperitoneal lymphadenectomy revealed intra‐renal vein involvement with a prominent teratomatous component. Conclusion Defining the exact extent of malignant lesions, especially endovascular lesions, is very important to clarify how advanced the malignant lesions are. The surgeons must be aware of the risk factors that predict vascular involvement, and therefore, providing intraoperative access to vascular surgery procedures when needed.https://doi.org/10.1002/cnr2.1910mixed germ cell tumorrenal vein thrombosisteratomatesticular neoplasms |
| spellingShingle | Hamidreza Ghorbani Ali Emadi Torghabeh Mahdi Farzadnia Alireza Golshan Parisa Rabiei Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario Cancer Reports mixed germ cell tumor renal vein thrombosis teratoma testicular neoplasms |
| title | Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario |
| title_full | Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario |
| title_fullStr | Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario |
| title_full_unstemmed | Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario |
| title_short | Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario |
| title_sort | renal vein thrombosis due to metastatic germ cell tumor report of a case with a very rare clinical scenario |
| topic | mixed germ cell tumor renal vein thrombosis teratoma testicular neoplasms |
| url | https://doi.org/10.1002/cnr2.1910 |
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