Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition
Supramolecular hydrogels formed by self-assembly of low-molecular-weight amphiphiles (hydrogelators) have attracted significant attention, as smart and soft materials. However, most of the observed stimuli-responsive behaviour of these supramolecular hydrogels are limited to gel–sol transitions. In...
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| Format: | Article |
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MDPI AG
2021-02-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/4/1860 |
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| author | Naoki Tsutsumi Akitaka Ito Azumi Ishigamori Masato Ikeda Masayuki Izumi Rika Ochi |
| author_facet | Naoki Tsutsumi Akitaka Ito Azumi Ishigamori Masato Ikeda Masayuki Izumi Rika Ochi |
| author_sort | Naoki Tsutsumi |
| collection | DOAJ |
| description | Supramolecular hydrogels formed by self-assembly of low-molecular-weight amphiphiles (hydrogelators) have attracted significant attention, as smart and soft materials. However, most of the observed stimuli-responsive behaviour of these supramolecular hydrogels are limited to gel–sol transitions. In this study, we present bola-amphiphilic glycosylated lipopeptide-type supramolecular hydrogelators that exhibit reversible thermochromism along with a gel–sol transition. The bola-amphiphiles have mono-, di-, tri- or tetra-phenylalanine (F) as a short peptide moiety. We investigate and discuss the effects of the number of F residues on the gelation ability and the morphology of the self-assembled nanostructures. |
| first_indexed | 2024-03-09T00:55:36Z |
| format | Article |
| id | doaj.art-6d7719b780be4400af8134e6d0e5766b |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T00:55:36Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-6d7719b780be4400af8134e6d0e5766b2023-12-11T16:55:35ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-02-01224186010.3390/ijms22041860Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol TransitionNaoki Tsutsumi0Akitaka Ito1Azumi Ishigamori2Masato Ikeda3Masayuki Izumi4Rika Ochi5Graduate School of Integrated Arts and Sciences, Kochi University, 2-5-1, Akebono-cho, Kochi 780-8520, JapanSchool of Environmental Science and Engineering, Kochi University of Technology, Kami, Kochi 782-8502, JapanFaculty of Science, Kochi University, 2-5-1, Akebono-cho, Kochi 780-8520, JapanDepartment of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanGraduate School of Integrated Arts and Sciences, Kochi University, 2-5-1, Akebono-cho, Kochi 780-8520, JapanGraduate School of Integrated Arts and Sciences, Kochi University, 2-5-1, Akebono-cho, Kochi 780-8520, JapanSupramolecular hydrogels formed by self-assembly of low-molecular-weight amphiphiles (hydrogelators) have attracted significant attention, as smart and soft materials. However, most of the observed stimuli-responsive behaviour of these supramolecular hydrogels are limited to gel–sol transitions. In this study, we present bola-amphiphilic glycosylated lipopeptide-type supramolecular hydrogelators that exhibit reversible thermochromism along with a gel–sol transition. The bola-amphiphiles have mono-, di-, tri- or tetra-phenylalanine (F) as a short peptide moiety. We investigate and discuss the effects of the number of F residues on the gelation ability and the morphology of the self-assembled nanostructures.https://www.mdpi.com/1422-0067/22/4/1860self-assemblypeptidesupramolecular hydrogelchromism |
| spellingShingle | Naoki Tsutsumi Akitaka Ito Azumi Ishigamori Masato Ikeda Masayuki Izumi Rika Ochi Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition International Journal of Molecular Sciences self-assembly peptide supramolecular hydrogel chromism |
| title | Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition |
| title_full | Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition |
| title_fullStr | Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition |
| title_full_unstemmed | Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition |
| title_short | Synthesis and Self-Assembly Properties of Bola-Amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel–Sol Transition |
| title_sort | synthesis and self assembly properties of bola amphiphilic glycosylated lipopeptide type supramolecular hydrogels showing colour changes along with gel sol transition |
| topic | self-assembly peptide supramolecular hydrogel chromism |
| url | https://www.mdpi.com/1422-0067/22/4/1860 |
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