Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma

Rho-kinase inhibitors have been identified as a class of potential drugs for treating asthma because of their ability to reduce airway inflammation and active force in airway smooth muscle (ASM). Past research has revealed that, besides the effect on the ASM’s force generation, rho-kinase (ROCK) als...

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Bibliographic Details
Main Authors: Yuto Yasuda, Lu Wang, Pasquale Chitano, Chun Y. Seow
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/2/115