Silver(I) and Copper(II) 1,10-Phenanthroline-5,6-dione Complexes as Promising Antivirulence Strategy against <i>Leishmania</i>: Focus on Gp63 (Leishmanolysin)

Silver(I) and Copper(II) 1,10-Phenanthroline-5,6-dione Complexes as Promising Antivirulence Strategy against <i>Leishmania</i>: Focus on Gp63 (Leishmanolysin)

Leishmaniasis, caused by protozoa of the genus <i>Leishmania</i>, encompasses a group of neglected diseases with diverse clinical and epidemiological manifestations that can be fatal if not adequately and promptly managed/treated. The current chemotherapy options for this disease are exp...

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Bibliographic Details
Main Authors: Simone S. C. Oliveira, Claudyane A. Correia, Vanessa S. Santos, Elaine F. F. da Cunha, Alexandre A. de Castro, Teodorico C. Ramalho, Michael Devereux, Malachy McCann, Marta H. Branquinha, André L. S. Santos
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Tropical Medicine and Infectious Disease
Subjects:
<i>Leishmania amazonensis</i>
alternative chemotherapy
antivirulence strategy
coordination compounds
gp63
virulence
Online Access:https://www.mdpi.com/2414-6366/8/7/348

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