Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression
Recently carbon spinal implants have been introduced in the treatment of patients with metastatic spinal cord compression (MSCC). This is expected to decrease the deflection of radiation and improve diagnostic imaging and radiotherapy when compared to titanium implants. The aim of this study was to...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/16/4/736 |
| _version_ | 1797298694988496896 |
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| author | Søren Schmidt Morgen Emma Benedikte Alfthan Madsen Anders Skive Weiland Benny Dahl Martin Gehrchen |
| author_facet | Søren Schmidt Morgen Emma Benedikte Alfthan Madsen Anders Skive Weiland Benny Dahl Martin Gehrchen |
| author_sort | Søren Schmidt Morgen |
| collection | DOAJ |
| description | Recently carbon spinal implants have been introduced in the treatment of patients with metastatic spinal cord compression (MSCC). This is expected to decrease the deflection of radiation and improve diagnostic imaging and radiotherapy when compared to titanium implants. The aim of this study was to determine the safety and effectiveness of spinal carbon instrumentation (CI) in patients with MSCC in a large cohort study. A total of 163 patients received instrumentation between 1 January 2017 and 31 December 2021. A total of 80 were stabilized with CI and 83 with TI. The outcome measures were surgical revision, postsurgical survival, peri-operative bleeding, and surgery time. The peri-operative blood loss in the CI-group was significantly lower than that in the TI-group: 450mL vs. 630mL, (<i>p</i> = 0.02). There were no significant differences between the groups in mean survival (CI 9.9) vs. (TI 12.9) months (<i>p</i> = 0.39), or the number of patients needing a revision (CI 6) vs. (TI 10), (<i>p</i> = 0.39). The median duration of surgery was 121 min, (<i>p</i> = 0.99) with no significant difference between the two groups. Surgical treatment with CI for MSCC is safe and an equally sufficient treatment when compared to TI. |
| first_indexed | 2024-03-07T22:38:39Z |
| format | Article |
| id | doaj.art-6d80eca1a814410bb05477c826b89c19 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-07T22:38:39Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-6d80eca1a814410bb05477c826b89c192024-02-23T15:10:44ZengMDPI AGCancers2072-66942024-02-0116473610.3390/cancers16040736Carbon Instrumentation in Patients with Metastatic Spinal Cord CompressionSøren Schmidt Morgen0Emma Benedikte Alfthan Madsen1Anders Skive Weiland2Benny Dahl3Martin Gehrchen4Spine Unit, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, DenmarkSpine Unit, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, DenmarkSpine Unit, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, DenmarkSpine Unit, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, DenmarkSpine Unit, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, DenmarkRecently carbon spinal implants have been introduced in the treatment of patients with metastatic spinal cord compression (MSCC). This is expected to decrease the deflection of radiation and improve diagnostic imaging and radiotherapy when compared to titanium implants. The aim of this study was to determine the safety and effectiveness of spinal carbon instrumentation (CI) in patients with MSCC in a large cohort study. A total of 163 patients received instrumentation between 1 January 2017 and 31 December 2021. A total of 80 were stabilized with CI and 83 with TI. The outcome measures were surgical revision, postsurgical survival, peri-operative bleeding, and surgery time. The peri-operative blood loss in the CI-group was significantly lower than that in the TI-group: 450mL vs. 630mL, (<i>p</i> = 0.02). There were no significant differences between the groups in mean survival (CI 9.9) vs. (TI 12.9) months (<i>p</i> = 0.39), or the number of patients needing a revision (CI 6) vs. (TI 10), (<i>p</i> = 0.39). The median duration of surgery was 121 min, (<i>p</i> = 0.99) with no significant difference between the two groups. Surgical treatment with CI for MSCC is safe and an equally sufficient treatment when compared to TI.https://www.mdpi.com/2072-6694/16/4/736spine surgerymetastatic spinal cord compressionspinal metastasiscancer treatment |
| spellingShingle | Søren Schmidt Morgen Emma Benedikte Alfthan Madsen Anders Skive Weiland Benny Dahl Martin Gehrchen Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression Cancers spine surgery metastatic spinal cord compression spinal metastasis cancer treatment |
| title | Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression |
| title_full | Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression |
| title_fullStr | Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression |
| title_full_unstemmed | Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression |
| title_short | Carbon Instrumentation in Patients with Metastatic Spinal Cord Compression |
| title_sort | carbon instrumentation in patients with metastatic spinal cord compression |
| topic | spine surgery metastatic spinal cord compression spinal metastasis cancer treatment |
| url | https://www.mdpi.com/2072-6694/16/4/736 |
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