Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review

Objective This study reviewed the current evidence on the clinical characteristics and outcome of acute pancreatitis (AP) following spinal surgery. Methods A systematic search was performed to identify English articles published through May 2020 in PubMed, Scopus, EMBASE, Latin American & Caribb...

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Main Authors: Ravindri Jayasinghe, Sonali Ranasinghe, Chandrani Kuruppu, Umesh Jayarajah, Sanjeewa Seneviratne
Format: Article
Language:English
Published: SAGE Publishing 2022-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221121950
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author Ravindri Jayasinghe
Sonali Ranasinghe
Chandrani Kuruppu
Umesh Jayarajah
Sanjeewa Seneviratne
author_facet Ravindri Jayasinghe
Sonali Ranasinghe
Chandrani Kuruppu
Umesh Jayarajah
Sanjeewa Seneviratne
author_sort Ravindri Jayasinghe
collection DOAJ
description Objective This study reviewed the current evidence on the clinical characteristics and outcome of acute pancreatitis (AP) following spinal surgery. Methods A systematic search was performed to identify English articles published through May 2020 in PubMed, Scopus, EMBASE, Latin American & Caribbean Health Sciences Literature, and Cochrane Library. Data on clinical characteristics, risk factors, and outcomes were analyzed. Results Eleven papers (including six case reports) were included, with 306 patients (incidence, 23.0%) developing AP after spinal surgery (mean age, 14.2 years). Of the studies that specified symptoms (55 patients), abdominal pain (43.6%), nausea and vomiting (32.7%), and abdominal distension (7.27%) were most prevalent. The mean duration from surgery to symptom onset was 6.15 days (range, 1–7). The most common complications of AP were glucose intolerance (25%), peritonitis (2%), pseudocyst formation (2%), and fluid collection (2%) were most prevalent. Prolonged fasting time (13.6%), intraoperative blood loss (9.09%), gastroesophageal reflux disease (9.1%), age >14 years (9.1%), and low BMI (9.1%) were most commonly associated with AP. Two deaths (0.6%) were reported. Conclusion AP remains an important complication of spinal surgery because of its morbidity and mortality. Avoiding major risk factors can reduce the incidence of AP following spinal surgery.
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spelling doaj.art-6d8109525b1b4319b4964964fb5fb05a2022-12-22T04:30:48ZengSAGE PublishingJournal of International Medical Research1473-23002022-09-015010.1177/03000605221121950Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic reviewRavindri JayasingheSonali RanasingheChandrani KuruppuUmesh JayarajahSanjeewa SeneviratneObjective This study reviewed the current evidence on the clinical characteristics and outcome of acute pancreatitis (AP) following spinal surgery. Methods A systematic search was performed to identify English articles published through May 2020 in PubMed, Scopus, EMBASE, Latin American & Caribbean Health Sciences Literature, and Cochrane Library. Data on clinical characteristics, risk factors, and outcomes were analyzed. Results Eleven papers (including six case reports) were included, with 306 patients (incidence, 23.0%) developing AP after spinal surgery (mean age, 14.2 years). Of the studies that specified symptoms (55 patients), abdominal pain (43.6%), nausea and vomiting (32.7%), and abdominal distension (7.27%) were most prevalent. The mean duration from surgery to symptom onset was 6.15 days (range, 1–7). The most common complications of AP were glucose intolerance (25%), peritonitis (2%), pseudocyst formation (2%), and fluid collection (2%) were most prevalent. Prolonged fasting time (13.6%), intraoperative blood loss (9.09%), gastroesophageal reflux disease (9.1%), age >14 years (9.1%), and low BMI (9.1%) were most commonly associated with AP. Two deaths (0.6%) were reported. Conclusion AP remains an important complication of spinal surgery because of its morbidity and mortality. Avoiding major risk factors can reduce the incidence of AP following spinal surgery.https://doi.org/10.1177/03000605221121950
spellingShingle Ravindri Jayasinghe
Sonali Ranasinghe
Chandrani Kuruppu
Umesh Jayarajah
Sanjeewa Seneviratne
Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
Journal of International Medical Research
title Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
title_full Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
title_fullStr Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
title_full_unstemmed Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
title_short Clinical characteristics and outcomes of acute pancreatitis following spinal surgery: a systematic review
title_sort clinical characteristics and outcomes of acute pancreatitis following spinal surgery a systematic review
url https://doi.org/10.1177/03000605221121950
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