Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia
Abstract Background Paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic progressive granulomatous enteritis mainly affecting domestic and wild ruminants worldwide. Although paratuberculosis could be prevail in Ethiopia, there is a scarcity of epidemiological d...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Veterinary Research |
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| Online Access: | https://doi.org/10.1186/s12917-023-03725-x |
| _version_ | 1797452239994880000 |
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| author | Temesgen Mohammed Gezahegne Mamo Aboma Zewude Asegedech Sirak Balako Gumi Gobena Ameni |
| author_facet | Temesgen Mohammed Gezahegne Mamo Aboma Zewude Asegedech Sirak Balako Gumi Gobena Ameni |
| author_sort | Temesgen Mohammed |
| collection | DOAJ |
| description | Abstract Background Paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic progressive granulomatous enteritis mainly affecting domestic and wild ruminants worldwide. Although paratuberculosis could be prevail in Ethiopia, there is a scarcity of epidemiological data on paratuberculosis in the country. Thus, this study was conducted to estimate the prevalence of paratuberculosis based on gross and microscopic lesions in cattle slaughtered at ELFORA Abattoir, central Ethiopia. Small intestines and associated lymph nodes of 400 apparently healthy cattle which were slaughtered at ELFORA export abattoir were examined for gross and microscopic lesions of paratuberculosis. The microscopic lesions were classified into four grades (I-IV) based on the type and number of cells infiltrated into the lesion. The prevalence of paratuberculosis was estimated on the basis of gross as well as microscopic lesion of paratuberculosis. Results The prevalence of paratuberculosis was 11.25% (95% Confidence interval, CI = 0.083–0.148) on the basis of gross lesion. However, relatively lower prevalence (2.0%, 95% CI = 0.01, 0.039) was recorded based on microscopic lesion. The gross lesions were characterized by intestinal thickening, mucosal corrugations and enlargement of associated mesenteric lymph nodes. On the other hand, the microscopic lesions were characterized by granuloma of different grades ranging from grade I to grade III lesions. Conclusions The present study indicated the occurrence of paratuberculosis in cattle of Ethiopia based on the detection of gross and microscopic lesions consistent with the lesion of paratuberculosis. The result of this study could be used as baseline information for future studies on the epidemiology and economic significance of paratuberculosis. |
| first_indexed | 2024-03-09T15:05:55Z |
| format | Article |
| id | doaj.art-6d810cf3370446919c4a6baa5d26de92 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-03-09T15:05:55Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-6d810cf3370446919c4a6baa5d26de922023-11-26T13:38:01ZengBMCBMC Veterinary Research1746-61482023-10-011911810.1186/s12917-023-03725-xPrevalence of paratuberculosis in cattle based on gross and microscopic lesions in EthiopiaTemesgen Mohammed0Gezahegne Mamo1Aboma Zewude2Asegedech Sirak3Balako Gumi4Gobena Ameni5Aklilu Lemma Institute of Pathobiology, Addis Ababa UniversityCollege of Veterinary Medicine and Agriculture, Addis Ababa UniversityAklilu Lemma Institute of Pathobiology, Addis Ababa UniversityNational Animal Health Diagnostic and Investigation CenterAklilu Lemma Institute of Pathobiology, Addis Ababa UniversityAklilu Lemma Institute of Pathobiology, Addis Ababa UniversityAbstract Background Paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic progressive granulomatous enteritis mainly affecting domestic and wild ruminants worldwide. Although paratuberculosis could be prevail in Ethiopia, there is a scarcity of epidemiological data on paratuberculosis in the country. Thus, this study was conducted to estimate the prevalence of paratuberculosis based on gross and microscopic lesions in cattle slaughtered at ELFORA Abattoir, central Ethiopia. Small intestines and associated lymph nodes of 400 apparently healthy cattle which were slaughtered at ELFORA export abattoir were examined for gross and microscopic lesions of paratuberculosis. The microscopic lesions were classified into four grades (I-IV) based on the type and number of cells infiltrated into the lesion. The prevalence of paratuberculosis was estimated on the basis of gross as well as microscopic lesion of paratuberculosis. Results The prevalence of paratuberculosis was 11.25% (95% Confidence interval, CI = 0.083–0.148) on the basis of gross lesion. However, relatively lower prevalence (2.0%, 95% CI = 0.01, 0.039) was recorded based on microscopic lesion. The gross lesions were characterized by intestinal thickening, mucosal corrugations and enlargement of associated mesenteric lymph nodes. On the other hand, the microscopic lesions were characterized by granuloma of different grades ranging from grade I to grade III lesions. Conclusions The present study indicated the occurrence of paratuberculosis in cattle of Ethiopia based on the detection of gross and microscopic lesions consistent with the lesion of paratuberculosis. The result of this study could be used as baseline information for future studies on the epidemiology and economic significance of paratuberculosis.https://doi.org/10.1186/s12917-023-03725-xParatuberculosisPrevalencePathologyCattleEthiopia |
| spellingShingle | Temesgen Mohammed Gezahegne Mamo Aboma Zewude Asegedech Sirak Balako Gumi Gobena Ameni Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia BMC Veterinary Research Paratuberculosis Prevalence Pathology Cattle Ethiopia |
| title | Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia |
| title_full | Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia |
| title_fullStr | Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia |
| title_full_unstemmed | Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia |
| title_short | Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia |
| title_sort | prevalence of paratuberculosis in cattle based on gross and microscopic lesions in ethiopia |
| topic | Paratuberculosis Prevalence Pathology Cattle Ethiopia |
| url | https://doi.org/10.1186/s12917-023-03725-x |
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