Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells

Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells

Plasma concentrations of a pleiotropic cytokine, interleukin (IL)-6, are increased in patients with cardiac myxoma. We investigated the regulation of IL-6 in cardiac myxoma. Immunohistochemical staining and reverse transcription-polymerase chain reaction (RT-PCR) revealed that IL-6 and its receptors...

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Bibliographic Details
Main Authors: Michihisa Jougasaki, Yoko Takenoshita, Katsuyuki Umebashi, Masayoshi Yamamoto, Ku Sudou, Hitoshi Nakashima, Masahiro Sonoda, Tamahiro Kinjo
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
myxoma
interleukin-6
autocrine
STAT3
Akt
Online Access:https://www.mdpi.com/1422-0067/25/4/2232

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