Deletion of the Mycobacterium tuberculosis cyp138 gene leads to changes in membrane-related lipid composition and antibiotic susceptibility

Deletion of the Mycobacterium tuberculosis cyp138 gene leads to changes in membrane-related lipid composition and antibiotic susceptibility

IntroductionMycobacterium tuberculosis (Mtb), the main cause of tuberculosis (TB), has brought a great burden to the world's public health. With the widespread use of Mtb drug-resistant strains, the pressure on anti-TB treatment is increasing. Anti-TB drugs with novel structures and targets are...

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Bibliographic Details
Main Authors: Yun Lu, Hongtong Chen, Zhiyuan Shao, Lang Sun, Congran Li, Yu Lu, Xuefu You, Xinyi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
CYP138
gene knock-out
membrane-related lipids
antibiotics susceptibility
triacylglycerol
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1301204/full

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