Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review
The human body is colonized from the birth by a large number of microorganisms. This will constitute a real “functional microbial organ” that is fundamental for homeostasis and therefore for health in humans. Those microorganisms. The microbial populations that colonize humans creating a specific ec...
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| Format: | Article |
| Language: | English |
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IMR Press
2021-05-01
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| Series: | Frontiers in Bioscience-Landmark |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/FBL/26/6/10.52586/4930 |
| _version_ | 1831734813371924480 |
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| author | Luigi Santacroce Adrian Man Ioannis Alexandros Charitos Kastriot Haxhirexha Skender Topi |
| author_facet | Luigi Santacroce Adrian Man Ioannis Alexandros Charitos Kastriot Haxhirexha Skender Topi |
| author_sort | Luigi Santacroce |
| collection | DOAJ |
| description | The human body is colonized from the birth by a large number of microorganisms. This will constitute a real “functional microbial organ” that is fundamental for homeostasis and therefore for health in humans. Those microorganisms. The microbial populations that colonize humans creating a specific ecosystem they have been collectively referred to as “human microbiota” or “human normal microflora”. The microbiota play an important pathophysiological role in the various locations of the human body. This article focuses on one of the most important, that is the enteric microbiota. The composition (quantitative and qualitative) of microbes is analyzed in relation to age and environment during the course of human life. It also highlights eubiosis and dysbiosis as key terms for its role in health and disease. Finally, it analyzes its bi-directional relationship with the microbiota of the lungs, skin and that of the brain, and consequently for the whole central and peripheral nervous system for the maintenance of health in the human body. |
| first_indexed | 2024-12-21T12:15:23Z |
| format | Article |
| id | doaj.art-6d83659a59dc4481b53327b4f1a7be0d |
| institution | Directory Open Access Journal |
| issn | 2768-6701 |
| language | English |
| last_indexed | 2024-12-21T12:15:23Z |
| publishDate | 2021-05-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Frontiers in Bioscience-Landmark |
| spelling | doaj.art-6d83659a59dc4481b53327b4f1a7be0d2022-12-21T19:04:27ZengIMR PressFrontiers in Bioscience-Landmark2768-67012021-05-0126613514810.52586/4930s1093-9946(21)04614-2Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative reviewLuigi Santacroce0Adrian Man1Ioannis Alexandros Charitos2Kastriot Haxhirexha3Skender Topi4Department of Interdisciplinary Medicine, Microbiology and Virology Unit, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Microbiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540003 Târgu Mureș, RomaniaEmergency/Urgent Department - National Poisoning Center, Riuniti University Hospital of Foggia, 85025 Foggia, ItalyMedical Faculty, Clinical Hospital of Tetovo, University of Tetovo, 1230 Tetovo, North MacedoniaSchool of Technical Medical Sciences, “Alexander Xhuvani” University of Elbasan, 3001-3006 Elbasan, AlbaniaThe human body is colonized from the birth by a large number of microorganisms. This will constitute a real “functional microbial organ” that is fundamental for homeostasis and therefore for health in humans. Those microorganisms. The microbial populations that colonize humans creating a specific ecosystem they have been collectively referred to as “human microbiota” or “human normal microflora”. The microbiota play an important pathophysiological role in the various locations of the human body. This article focuses on one of the most important, that is the enteric microbiota. The composition (quantitative and qualitative) of microbes is analyzed in relation to age and environment during the course of human life. It also highlights eubiosis and dysbiosis as key terms for its role in health and disease. Finally, it analyzes its bi-directional relationship with the microbiota of the lungs, skin and that of the brain, and consequently for the whole central and peripheral nervous system for the maintenance of health in the human body.https://www.imrpress.com/journal/FBL/26/6/10.52586/4930human microbiotamicrobiologygut microbiotadysbiosisimmune modulationgut-lung axisgut-brain axisgut-skin axisirritable bowel syndrome (ibs)idiopathic inflammatory bowel disease (ibd)colon cancermetabolic diseasessars-cov-2 |
| spellingShingle | Luigi Santacroce Adrian Man Ioannis Alexandros Charitos Kastriot Haxhirexha Skender Topi Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review Frontiers in Bioscience-Landmark human microbiota microbiology gut microbiota dysbiosis immune modulation gut-lung axis gut-brain axis gut-skin axis irritable bowel syndrome (ibs) idiopathic inflammatory bowel disease (ibd) colon cancer metabolic diseases sars-cov-2 |
| title | Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review |
| title_full | Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review |
| title_fullStr | Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review |
| title_full_unstemmed | Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review |
| title_short | Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review |
| title_sort | current knowledge about the connection between health status and gut microbiota from birth to elderly a narrative review |
| topic | human microbiota microbiology gut microbiota dysbiosis immune modulation gut-lung axis gut-brain axis gut-skin axis irritable bowel syndrome (ibs) idiopathic inflammatory bowel disease (ibd) colon cancer metabolic diseases sars-cov-2 |
| url | https://www.imrpress.com/journal/FBL/26/6/10.52586/4930 |
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