Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion
Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. Methods: Forty-six patients with RAO and fi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Knowledge E
2020-04-01
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| Series: | Journal of Ophthalmic & Vision Research |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/jovr.v15i2.6737 |
| _version_ | 1811333190999080960 |
|---|---|
| author | Mahmut Atum Gürsoy Alagöz |
| author_facet | Mahmut Atum Gürsoy Alagöz |
| author_sort | Mahmut Atum |
| collection | DOAJ |
| description | Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them.
Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated.
Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P
>
0.05). Patients with RAO had significantly increased NLR values (2.85
±
1.70) than the control subjects (1.63
±
0.59, P < 0.001). The mean PLR in patients with RAO was 123.69
±
64.98, while that in control subjects was 103.08
±
36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001).
Conclusion: NLRs were significantly increased in patients with RAO compared to the
control subjects. |
| first_indexed | 2024-04-13T16:48:25Z |
| format | Article |
| id | doaj.art-6d84a188c8114b0d973667be73041f64 |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-13T16:48:25Z |
| publishDate | 2020-04-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-6d84a188c8114b0d973667be73041f642022-12-22T02:39:00ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2020-04-011519520010.18502/jovr.v15i2.6737Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery OcclusionMahmut Atum0Gürsoy Alagöz1 Department of Ophthalmology, Sakarya University Education and Research Hospital, Adnan Menderes Caddesi Saglik Sokak, Sakarya, Turkey Department of Ophthalmology, Sakarya University Education and Research Hospital, Adnan Menderes Caddesi Saglik Sokak, Sakarya, Turkey Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated. Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P > 0.05). Patients with RAO had significantly increased NLR values (2.85 ± 1.70) than the control subjects (1.63 ± 0.59, P < 0.001). The mean PLR in patients with RAO was 123.69 ± 64.98, while that in control subjects was 103.08 ± 36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001). Conclusion: NLRs were significantly increased in patients with RAO compared to the control subjects.https://doi.org/10.18502/jovr.v15i2.6737hemogramneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratioretinal artery occlusionretinal vessels |
| spellingShingle | Mahmut Atum Gürsoy Alagöz Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion Journal of Ophthalmic & Vision Research hemogram neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio retinal artery occlusion retinal vessels |
| title | Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion |
| title_full | Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion |
| title_fullStr | Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion |
| title_full_unstemmed | Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion |
| title_short | Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion |
| title_sort | neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with retinal artery occlusion |
| topic | hemogram neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio retinal artery occlusion retinal vessels |
| url | https://doi.org/10.18502/jovr.v15i2.6737 |
| work_keys_str_mv | AT mahmutatum neutrophiltolymphocyteratioandplatelettolymphocyteratioinpatientswithretinalarteryocclusion AT gursoyalagoz neutrophiltolymphocyteratioandplatelettolymphocyteratioinpatientswithretinalarteryocclusion |