Broadening the biocompatibility of gold nanorods from rat to Macaca fascicularis: advancing clinical potential

Broadening the biocompatibility of gold nanorods from rat to Macaca fascicularis: advancing clinical potential

Abstract Background The biomedical field has used gold nanorods (GNRs) for decades; however, clinical trials and translation is limited except gold nanoshells. The preparation of gold nanoshells is more complex than that of polyethylene glycol-modified GNRs (PEG-GNRs), and it is difficult to ensure...

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Bibliographic Details
Main Authors: Jinfeng Liao, Taorang Tian, Sirong Shi, Xueping Xie, Shuanglin Peng, Ying Zhu, Jingang Xiao, Yunfeng Lin
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Nanobiotechnology
Subjects:
Gold nanorods
Systemic biocompatibility
Macaca fascicularis
Blood clearance
Biodistribution
Major organ analysis
Online Access:https://doi.org/10.1186/s12951-021-00941-1

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