Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate
Bacterial exopolysaccharide (EPS) is a secondary metabolite that is synthesized and secreted outside the cell wall during bacterial growth and metabolism. It can regulate the initial attachment of cells to different substrates and protect cells against environmental stress and dehydration. As a pote...
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| Format: | Article |
| Language: | zho |
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The editorial department of Science and Technology of Food Industry
2023-05-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060142 |
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| author | Liansheng YU Jingping GE Wenxiang PING Renpeng DU |
| author_facet | Liansheng YU Jingping GE Wenxiang PING Renpeng DU |
| author_sort | Liansheng YU |
| collection | DOAJ |
| description | Bacterial exopolysaccharide (EPS) is a secondary metabolite that is synthesized and secreted outside the cell wall during bacterial growth and metabolism. It can regulate the initial attachment of cells to different substrates and protect cells against environmental stress and dehydration. As a potential prebiotic, EPS has the characteristics of safety, non-toxicity and unique physical and chemical properties, and is widely used in the fields of food, medicine, biology and industry. However, the bacterial metabolic system is complex, and the biosynthetic mechanism of EPS has not been fully elucidated. Cyclic diguanylate (c-di-GMP) is an important second messenger, and it plays an important role in the regulation of many physiological activities such as biofilm formation, motility, adhesion, virulence and EPS synthesis. The analysis of the transcriptional regulation mechanism of c-di-GMP provides a new idea for exploring the biosynthesis mechanism of bacterial EPS. This paper summarizes the characteristics and synthetic degradation pathways of c-di-GMP in detail, and focuses on the regulatory mechanism of c-di-GMP in the process of bacterial EPS biosynthesis. This paper provides a theoretical basis for revealing the mechanism of bacterial EPS biosynthesis and the structure-activity relationship. |
| first_indexed | 2024-03-12T13:33:21Z |
| format | Article |
| id | doaj.art-6d903073ece544d48f7ec65b16d13451 |
| institution | Directory Open Access Journal |
| issn | 1002-0306 |
| language | zho |
| last_indexed | 2024-03-12T13:33:21Z |
| publishDate | 2023-05-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj.art-6d903073ece544d48f7ec65b16d134512023-08-24T06:01:47ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-05-0144942243010.13386/j.issn1002-0306.20220601422022060142-9Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic DiguanylateLiansheng YU0Jingping GE1Wenxiang PING2Renpeng DU3School of Life Sciences, Heilongjiang University, Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region, Key Laboratory of Microbiology, College of Heilongjiang Province, Harbin 150080, ChinaSchool of Life Sciences, Heilongjiang University, Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region, Key Laboratory of Microbiology, College of Heilongjiang Province, Harbin 150080, ChinaSchool of Life Sciences, Heilongjiang University, Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region, Key Laboratory of Microbiology, College of Heilongjiang Province, Harbin 150080, ChinaSchool of Life Sciences, Heilongjiang University, Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region, Key Laboratory of Microbiology, College of Heilongjiang Province, Harbin 150080, ChinaBacterial exopolysaccharide (EPS) is a secondary metabolite that is synthesized and secreted outside the cell wall during bacterial growth and metabolism. It can regulate the initial attachment of cells to different substrates and protect cells against environmental stress and dehydration. As a potential prebiotic, EPS has the characteristics of safety, non-toxicity and unique physical and chemical properties, and is widely used in the fields of food, medicine, biology and industry. However, the bacterial metabolic system is complex, and the biosynthetic mechanism of EPS has not been fully elucidated. Cyclic diguanylate (c-di-GMP) is an important second messenger, and it plays an important role in the regulation of many physiological activities such as biofilm formation, motility, adhesion, virulence and EPS synthesis. The analysis of the transcriptional regulation mechanism of c-di-GMP provides a new idea for exploring the biosynthesis mechanism of bacterial EPS. This paper summarizes the characteristics and synthetic degradation pathways of c-di-GMP in detail, and focuses on the regulatory mechanism of c-di-GMP in the process of bacterial EPS biosynthesis. This paper provides a theoretical basis for revealing the mechanism of bacterial EPS biosynthesis and the structure-activity relationship.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060142bacteriaexopolysaccharidebiosynthesiscyclic diguanylate |
| spellingShingle | Liansheng YU Jingping GE Wenxiang PING Renpeng DU Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate Shipin gongye ke-ji bacteria exopolysaccharide biosynthesis cyclic diguanylate |
| title | Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate |
| title_full | Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate |
| title_fullStr | Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate |
| title_full_unstemmed | Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate |
| title_short | Research Progress on Regulation of Bacterial Exopolysaccharide Biosynthesis by Cyclic Diguanylate |
| title_sort | research progress on regulation of bacterial exopolysaccharide biosynthesis by cyclic diguanylate |
| topic | bacteria exopolysaccharide biosynthesis cyclic diguanylate |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060142 |
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