US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules
The aim of the present study was to assess feasibility, safety and outcome of ultrasound (US) guided percutaneous radiofrequency (RF) ablation of large substernal benign thyroid nodules assisted by US-computed tomography (CT) fusion imaging and real-time virtual needle tracking (VT) system. Thirty p...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2022.2091167 |
| _version_ | 1811333949403693056 |
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| author | Davide Orlandi Umberto Viglino Giorgia Dedone Giacomo Leale Pietro Caruso Giovanni Mauri Giovanni Turtulici |
| author_facet | Davide Orlandi Umberto Viglino Giorgia Dedone Giacomo Leale Pietro Caruso Giovanni Mauri Giovanni Turtulici |
| author_sort | Davide Orlandi |
| collection | DOAJ |
| description | The aim of the present study was to assess feasibility, safety and outcome of ultrasound (US) guided percutaneous radiofrequency (RF) ablation of large substernal benign thyroid nodules assisted by US-computed tomography (CT) fusion imaging and real-time virtual needle tracking (VT) system. Thirty patients (18 females, mean age 56 y, range 32–76 y) with 35 benign nonfunctioning thyroid nodules (mean volume ± SD 26.8 ± 7.6 mL; range 20–38mL) were selected for CT-US fusion guided RF ablation. Nodules’ volume was evaluated before treatment and during 12-months follow-up. Complications’ rate was also evaluated. US-CT fusion imaging with VT system was feasible in all cases (feasibility 100%) and it was always possible to complete the procedure as planned (technical success 100%). Minor complications occurred in 2/30 cases (6.6%). No major complications occurred. 50% volume reduction (technique efficacy) was achieved in 93% cases, with a significant mean volume reduction at 12 months follow-up (68.7 ± 10.8%), (p < .001). The VT system could be useful in thyroid nodules ablation procedures assistance being able to track the RF electrode tip even when this is obscured by the bubbles produced by the ablative process. The combination of fusion imaging with VT assisted RF ablation represents a safe, non-surgical treatment option for patients with large substernal benign thyroid nodules. |
| first_indexed | 2024-04-13T17:00:27Z |
| format | Article |
| id | doaj.art-6d92e0b450c34aeb9a6d7345fe889460 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-04-13T17:00:27Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-6d92e0b450c34aeb9a6d7345fe8894602022-12-22T02:38:41ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-0139184785410.1080/02656736.2022.2091167US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodulesDavide Orlandi0Umberto Viglino1Giorgia Dedone2Giacomo Leale3Pietro Caruso4Giovanni Mauri5Giovanni Turtulici6Dipartimento di Radiologia e Ecografia Interventistica, Ospedale Evangelico Internazionale, Genova, ItalyScuola di Specializzazione in Radiodiagnostica, Università degli Studi di Genova, Genova, ItalyDipartimento di Radiologia e Ecografia Interventistica, Ospedale Evangelico Internazionale, Genova, ItalyDipartimento di Radiologia e Ecografia Interventistica, Ospedale Evangelico Internazionale, Genova, ItalyDipartimento di Radiologia e Ecografia Interventistica, Ospedale Evangelico Internazionale, Genova, ItalyDipartimento di Oncologia ed Emato-oncologia, Università degli studi di Milano, Milano, ItalyDipartimento di Radiologia e Ecografia Interventistica, Ospedale Evangelico Internazionale, Genova, ItalyThe aim of the present study was to assess feasibility, safety and outcome of ultrasound (US) guided percutaneous radiofrequency (RF) ablation of large substernal benign thyroid nodules assisted by US-computed tomography (CT) fusion imaging and real-time virtual needle tracking (VT) system. Thirty patients (18 females, mean age 56 y, range 32–76 y) with 35 benign nonfunctioning thyroid nodules (mean volume ± SD 26.8 ± 7.6 mL; range 20–38mL) were selected for CT-US fusion guided RF ablation. Nodules’ volume was evaluated before treatment and during 12-months follow-up. Complications’ rate was also evaluated. US-CT fusion imaging with VT system was feasible in all cases (feasibility 100%) and it was always possible to complete the procedure as planned (technical success 100%). Minor complications occurred in 2/30 cases (6.6%). No major complications occurred. 50% volume reduction (technique efficacy) was achieved in 93% cases, with a significant mean volume reduction at 12 months follow-up (68.7 ± 10.8%), (p < .001). The VT system could be useful in thyroid nodules ablation procedures assistance being able to track the RF electrode tip even when this is obscured by the bubbles produced by the ablative process. The combination of fusion imaging with VT assisted RF ablation represents a safe, non-surgical treatment option for patients with large substernal benign thyroid nodules.https://www.tandfonline.com/doi/10.1080/02656736.2022.2091167Substernal thyroid noduleradiofrequency ablationvirtual needle trackingfusion imaging |
| spellingShingle | Davide Orlandi Umberto Viglino Giorgia Dedone Giacomo Leale Pietro Caruso Giovanni Mauri Giovanni Turtulici US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules International Journal of Hyperthermia Substernal thyroid nodule radiofrequency ablation virtual needle tracking fusion imaging |
| title | US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| title_full | US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| title_fullStr | US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| title_full_unstemmed | US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| title_short | US-CT fusion-guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| title_sort | us ct fusion guided percutaneous radiofrequency ablation of large substernal benign thyroid nodules |
| topic | Substernal thyroid nodule radiofrequency ablation virtual needle tracking fusion imaging |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2022.2091167 |
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