Intraoperative biophotonic imaging systems for image-guided interventions

Biophotonic imaging has revolutionized the operation room by providing surgeons intraoperative image-guidance to diagnose tumors more efficiently and to resect tumors with real-time image navigation. Among many medical imaging modalities, near-infrared (NIR) light is ideal for image-guided surgery b...

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Main Authors: Sajedi Salar, Sabet Hamid, Choi Hak Soo
Format: Article
Language:English
Published: De Gruyter 2018-12-01
Series:Nanophotonics
Subjects:
Online Access:https://doi.org/10.1515/nanoph-2018-0134
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author Sajedi Salar
Sabet Hamid
Choi Hak Soo
author_facet Sajedi Salar
Sabet Hamid
Choi Hak Soo
author_sort Sajedi Salar
collection DOAJ
description Biophotonic imaging has revolutionized the operation room by providing surgeons intraoperative image-guidance to diagnose tumors more efficiently and to resect tumors with real-time image navigation. Among many medical imaging modalities, near-infrared (NIR) light is ideal for image-guided surgery because it penetrates relatively deeply into living tissue, while nuclear imaging provides quantitative and unlimited depth information. It is therefore ideal to develop an integrated imaging system by combining NIR fluorescence and gamma-positron imaging to provide surgeons with highly sensitive and quantitative detection of diseases, such as cancer, in real-time without changing the look of the surgical field. The focus of this review is to provide recent progress in intraoperative biophotonic imaging systems, NIR fluorescence imaging and intraoperative nuclear imaging devices, and their future perspectives for image-guided interventions.
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spelling doaj.art-6d937fdccfdb4b46ab548d457340432d2022-12-21T20:03:40ZengDe GruyterNanophotonics2192-86062192-86142018-12-01819911610.1515/nanoph-2018-0134nanoph-2018-0134Intraoperative biophotonic imaging systems for image-guided interventionsSajedi Salar0Sabet Hamid1Choi Hak Soo2Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USAGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USAGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USABiophotonic imaging has revolutionized the operation room by providing surgeons intraoperative image-guidance to diagnose tumors more efficiently and to resect tumors with real-time image navigation. Among many medical imaging modalities, near-infrared (NIR) light is ideal for image-guided surgery because it penetrates relatively deeply into living tissue, while nuclear imaging provides quantitative and unlimited depth information. It is therefore ideal to develop an integrated imaging system by combining NIR fluorescence and gamma-positron imaging to provide surgeons with highly sensitive and quantitative detection of diseases, such as cancer, in real-time without changing the look of the surgical field. The focus of this review is to provide recent progress in intraoperative biophotonic imaging systems, NIR fluorescence imaging and intraoperative nuclear imaging devices, and their future perspectives for image-guided interventions.https://doi.org/10.1515/nanoph-2018-0134intraoperative imagingbiophotonic imagingmultimodal imaginggamma-nir imagingimage-guided surgery
spellingShingle Sajedi Salar
Sabet Hamid
Choi Hak Soo
Intraoperative biophotonic imaging systems for image-guided interventions
Nanophotonics
intraoperative imaging
biophotonic imaging
multimodal imaging
gamma-nir imaging
image-guided surgery
title Intraoperative biophotonic imaging systems for image-guided interventions
title_full Intraoperative biophotonic imaging systems for image-guided interventions
title_fullStr Intraoperative biophotonic imaging systems for image-guided interventions
title_full_unstemmed Intraoperative biophotonic imaging systems for image-guided interventions
title_short Intraoperative biophotonic imaging systems for image-guided interventions
title_sort intraoperative biophotonic imaging systems for image guided interventions
topic intraoperative imaging
biophotonic imaging
multimodal imaging
gamma-nir imaging
image-guided surgery
url https://doi.org/10.1515/nanoph-2018-0134
work_keys_str_mv AT sajedisalar intraoperativebiophotonicimagingsystemsforimageguidedinterventions
AT sabethamid intraoperativebiophotonicimagingsystemsforimageguidedinterventions
AT choihaksoo intraoperativebiophotonicimagingsystemsforimageguidedinterventions